Human Recombinant TPM1-ALK, Active protein, GST Tag (V2LY-0526-LY7329)
Compare
Online Inquiry
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982).
Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Biological Process cardiac muscle contraction Source:BHF-UCL1 Publication
Biological Process cellular response to reactive oxygen species Source:BHF-UCL1 Publication
Biological Process cytoskeleton organization Source:BHF-UCL1 Publication
Biological Process muscle contraction Source:GO_Central1 Publication
Biological Process muscle filament sliding Source:BHF-UCLBy Similarity
Biological Process negative regulation of cell migration Source:BHF-UCLBy Similarity
Biological Process negative regulation of vascular associated smooth muscle cell migration Source:BHF-UCL1 Publication
Biological Process negative regulation of vascular associated smooth muscle cell proliferation Source:BHF-UCL1 Publication
Biological Process positive regulation of ATP-dependent activity Source:BHF-UCLBy Similarity
Biological Process positive regulation of cell adhesion Source:BHF-UCLBy Similarity
Biological Process positive regulation of heart rate by epinephrine Source:BHF-UCLBy Similarity
Biological Process positive regulation of stress fiber assembly Source:BHF-UCLBy Similarity
Biological Process regulation of cell shape Source:BHF-UCL1 Publication
Biological Process regulation of heart contraction Source:ProtInc1 Publication
Biological Process regulation of muscle contraction Source:ProtInc1 Publication
Biological Process ruffle organization Source:BHF-UCLBy Similarity
Biological Process sarcomere organization Source:BHF-UCL1 Publication
Biological Process ventricular cardiac muscle tissue morphogenesis Source:BHF-UCL1 Publication
Biological Process wound healing Source:BHF-UCLBy Similarity
Associates with F-actin stress fibers.
A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Cardiomyopathy, dilated 1Y (CMD1Y):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Left ventricular non-compaction 9 (LVNC9):
A form of left ventricular non-compaction, a cardiomyopathy due to myocardial morphogenesis arrest and characterized by a hypertrophic left ventricle, a severely thickened 2-layered myocardium, numerous prominent trabeculations, deep intertrabecular recesses, and poor systolic function. Clinical manifestations are variable. Some affected individuals experience no symptoms at all, others develop heart failure. In some cases, left ventricular non-compaction is associated with other congenital heart anomalies. LVNC9 is an autosomal dominant condition.
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant TPM1 protein, His Tag (CAT#: V2LY-0526-LY7328)
Related Products
Mouse Anti-TPM1 Recombinant Antibody (TM-33) (CAT#: CBMAB-T3825-YJ)
Mouse Anti-TPM1 Recombinant Antibody (TM-36) (CAT#: CBMAB-T3826-YJ)
Mouse Anti-TPM1 Antibody (CH106) (CAT#: CBMAB-1696CQ)
Mouse Anti-TPM1 Recombinant Antibody (SPM224) (CAT#: CBMAB-T3823-YJ)
Human Recombinant TPM1 protein, His Tag (CAT#: V2LY-0526-LY7328)
Mouse Anti-TPM1 Antibody (CH1) (CAT#: CBMAB-1695CQ)
Rabbit Anti-TPM1 Recombinant Antibody (CBYJT-4343) (CAT#: CBMAB-T3830-YJ)
Rabbit Anti-TPM1 Recombinant Antibody (CBYJT-4340) (CAT#: CBMAB-T3827-YJ)
Mouse Anti-TPM1 Recombinant Antibody (CBYJT-4339) (CAT#: CBMAB-T3824-YJ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
