Human Recombinant TSSK2, Active protein, GST Tag (V2LY-0526-LY7452)

Name: Human Recombinant TSSK2, Active protein, GST Tag
SKU: V2LY-0526-LY7452
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant TSSK2, Active protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 66 kDa.

Molecule Mass

66 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

testis-specific serine kinase 2

Function

Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.

Biological Process

Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein autophosphorylation Source:UniProtKB1 Publication
Biological Process protein phosphorylation Source:UniProtKB
Biological Process spermatid development Source:UniProtKB

Cellular Location

Cytoplasm
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity).
In spermatids, concentrates in centrioles during flagellogenesis

PTM

Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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