TSSK2

TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM
Full Name
testis-specific serine kinase 2
Function
Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
Biological Process
Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein autophosphorylation Source:UniProtKB1 Publication
Biological Process protein phosphorylation Source:UniProtKB
Biological Process spermatid development Source:UniProtKB
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity).
In spermatids, concentrates in centrioles during flagellogenesis
PTM
Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.
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Anti-TSSK2 antibodies

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Mouse Anti-TSSK2 Recombinant Antibody (1F6) (CBMAB-A9592-LY)

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Target: TSSK2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F6
Application*: WB, E
Datasheet SDS

Mouse Anti-TSSK2 Recombinant Antibody (1E12) (CBMAB-A9591-LY)

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Target: TSSK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E12
Application*: WB, E
Datasheet SDS

Mouse Anti-TSSK2 Recombinant Antibody (CBYJT-5101) (CBMAB-T4679-YJ)

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Target: TSSK2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-5101
Application*: WB
Datasheet SDS

Mouse Anti-TSSK2 Recombinant Antibody (CBYJT-5100) (CBMAB-T4678-YJ)

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Target: TSSK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-5100
Application*: IF, SE, E, WB, P
Datasheet SDS

Mouse Anti-TSSK2 Recombinant Antibody (CBYJT-5099) (CBMAB-T4677-YJ)

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Target: TSSK2
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human
Clone: CBYJT-5099
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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