Human Recombinant VEGFB protein, hFc Tag (V2LY-0526-LY7594)

Name: Human Recombinant VEGFB protein, hFc Tag
SKU: V2LY-0526-LY7594
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

hFc Tag

Protein Construction

This product is Human Recombinant VEGFB protein, hFc Tag consist of Amino Acid: 22-207 and predicts a molecular mass of 47.8 kDa.

Molecule Mass

47.8 kDa

Sequence

Amino Acid: 22-207

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Vascular Endothelial Growth Factor B

Function

Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.

Biological Process

Biological Process cardiac muscle contraction Source:Ensembl
Biological Process coronary vasculature development Source:Ensembl
Biological Process induction of positive chemotaxis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB
Biological Process negative regulation of gene expression Source:UniProtKB
Biological Process negative regulation of neuron apoptotic process Source:UniProtKB
Biological Process positive regulation of angiogenesis Source:GO_Central1 Publication
Biological Process positive regulation of cell division Source:UniProtKB-KW
Biological Process positive regulation of endothelial cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascade Source:UniProtKB
Biological Process positive regulation of mast cell chemotaxis Source:UniProtKB1 Publication
Biological Process positive regulation of peptidyl-tyrosine phosphorylation Source:UniProtKB
Biological Process positive regulation of protein kinase B signaling Source:UniProtKB
Biological Process positive regulation of protein phosphorylation Source:GO_Central1 Publication
Biological Process positive regulation of vascular endothelial growth factor receptor signaling pathway Source:UniProtKB
Biological Process positive regulation of vascular wound healing Source:UniProtKB
Biological Process protein O-linked glycosylation Source:Ensembl
Biological Process response to hypoxia Source:GO_Central1 Publication
Biological Process sprouting angiogenesis Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor receptor signaling pathway Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor signaling pathway Source:GO_Central1 Publication

Cellular Location

Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.

PTM

VEGF-B186 is O-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Vegfb ELISA Kit (CAT#: V2LY-0626-LY1061)

Mouse Vegfb ELISA Kit (CAT#: V2LY-0626-LY1083)

Human VEGFB ELISA Kit (CAT#: V2LY-0626-LY444)

VEGFB Matched Antibody Pair (1300) (CAT#: APMAB-1300LY)

Antibody Pairs

VEGFB Matched Antibody Pair (1300) (CAT#: APMAB-1300LY)

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Mouse Anti-VEGFB Recombinant Antibody (CBYY-1511) (CAT#: CBMAB-1579-YY)

Rat Anti-VEGFB Recombinant Antibody (CBYY-1503) (CAT#: CBMAB-1566-YY)

Rat Anti-VEGFB Recombinant Antibody (CBYY-1506) (CAT#: CBMAB-1571-YY)

Mouse Anti-VEGFB Recombinant Antibody (CBYY-1499) (CAT#: CBMAB-1562-YY)

Mouse Anti-VEGFB Recombinant Antibody (CBYY-1505) (CAT#: CBMAB-1570-YY)

Mouse Vegfb ELISA Kit (CAT#: V2LY-0626-LY1083)

Rat Anti-VEGFB Recombinant Antibody (CBYY-1502) (CAT#: CBMAB-1565-YY)

Mouse Anti-VEGFB Recombinant Antibody (CBXF-2093) (CAT#: CBMAB-F1095-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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