Human VEGFB ELISA Kit (V2LY-0626-LY444)

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Tested Data
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Basic Information

Sensitivity
0.01 ng/mL
Detection Range
0.02-1.2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
21.6 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Vascular Endothelial Growth Factor B
Function
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Biological Process
Biological Process cardiac muscle contraction Source:Ensembl
Biological Process coronary vasculature development Source:Ensembl
Biological Process induction of positive chemotaxis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB
Biological Process negative regulation of gene expression Source:UniProtKB
Biological Process negative regulation of neuron apoptotic process Source:UniProtKB
Biological Process positive regulation of angiogenesis Source:GO_Central1 Publication
Biological Process positive regulation of cell division Source:UniProtKB-KW
Biological Process positive regulation of endothelial cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascade Source:UniProtKB
Biological Process positive regulation of mast cell chemotaxis Source:UniProtKB1 Publication
Biological Process positive regulation of peptidyl-tyrosine phosphorylation Source:UniProtKB
Biological Process positive regulation of protein kinase B signaling Source:UniProtKB
Biological Process positive regulation of protein phosphorylation Source:GO_Central1 Publication
Biological Process positive regulation of vascular endothelial growth factor receptor signaling pathway Source:UniProtKB
Biological Process positive regulation of vascular wound healing Source:UniProtKB
Biological Process protein O-linked glycosylation Source:Ensembl
Biological Process response to hypoxia Source:GO_Central1 Publication
Biological Process sprouting angiogenesis Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor receptor signaling pathway Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor signaling pathway Source:GO_Central1 Publication
Cellular Location
Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
PTM
VEGF-B186 is O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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