Sign in or Register   Sign in or Register
  |  

Mouse Anti-Human Serum Albumin Recombinant Antibody (5G11-F5) (CBMAB-Z0443-LY)

The product is antibody recognizes Human Serum Albumin. The antibody 5G11-F5 immunoassay techniques such as: LFIA, ELISA.
See all Human Serum Albumin antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5G11-F5
Antibody Isotype
IgG1
Application
LFIA, ELISA

Basic Information

Immunogen
Native Human Serum Albumin.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.03% Proclin300.
Concentration
4.7 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Albumin
Entrez Gene ID
213
UniProt ID
P02768
Alternative Names
ALB; FDAH; ANALBA; PRO0883; PRO0903; PRO1341.
Function
Binds water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc> calcium> magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).
Biological Process
Cellular protein metabolic process Source: Reactome
Cellular response to starvation Source: UniProtKB
Heme biosynthetic process Source: Reactome
Heme catabolic process Source: Reactome
High-density lipoprotein particle remodeling Source: Reactome
Maintenance of mitochondrion location Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of programmed cell death Source: UniProtKB
Platelet degranulation Source: Reactome
Post-translational protein modification Source: Reactome
Receptor-mediated endocytosis Source: Reactome
Retina homeostasis Source: UniProtKB
Cellular Location
Secreted
Involvement in disease
Hyperthyroxinemia, familial dysalbuminemic (FDAH): A disorder characterized by abnormally elevated levels of total serum thyroxine (T4) in euthyroid patients. It is due to abnormal serum albumin that binds T4 with enhanced affinity.
Analbuminemia (ANALBA): A rare autosomal recessive disorder manifested by the presence of a very low amount of circulating serum albumin. Affected individuals manifest mild edema, hypotension, fatigue, and, occasionally, lower body lipodystrophy (mainly in adult females). The most common biochemical finding is hyperlipidemia, with a significant increase in the total and LDL cholesterol concentrations, but normal concentrations of HDL cholesterol and triglycerides.
PTM
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylated by FAM20C in the extracellular medium.
Acetylated on Lys-223 by acetylsalicylic acid.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-Human Serum Albumin Recombinant Antibody (5G11-F5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare