Human TIMM8A ELISA Kit (V2LY-0626-LY5931)

Name: Human TIMM8A ELISA Kit
SKU: V2LY-0626-LY5931
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Sensitivity

0.0096 ng/mL

Detection Range

0.02-3.5 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

11.0 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

translocase of inner mitochondrial membrane 8 homolog A (yeast)

Function

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Biological Process

Biological Process nervous system developmentSource:ProtInc1 Publication
Biological Process protein insertion into mitochondrial inner membraneSource:BHF-UCL1 Publication

Cellular Location

Mitochondrion inner membrane

Involvement in disease

Mohr-Tranebjaerg syndrome (MTS):
An X-linked recessive disorder characterized by postlingual sensorineural deafness with onset in early childhood, dystonia, spasticity, dysphagia, mental deterioration, paranoia and cortical blindness.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-TIMM8A Recombinant Antibody (9G347) (CAT#: CBMAB-D2276-YC)

Mouse Anti-TIMM8A Recombinant Antibody (2F11) (CAT#: CBMAB-A9102-LY)

Mouse Anti-TIMM8A (C-terminus) Recombinant Antibody (CBFYM-3157) (CAT#: CBMAB-M3354-FY)

Mouse Anti-TIMM8A Recombinant Antibody (CBYJT-3181) (CAT#: CBMAB-T2455-YJ)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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