ICAM1 Matched Antibody Pair (580) (APMAB-580LY)

Name: ICAM1 Matched Antibody Pair (580)
SKU: APMAB-580LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-ICAM1 polyclonal antibody, 100 ug

Detection Antibody

Anti-ICAM1 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Alternative Names

Intercellular Adhesion Molecule 1

Entrez Gene ID

3383

UniProt ID

P05362

More Infomation

Bai, X., Guo, Z. Q., Zhang, Y. P., Fan, Z. Z., Liu, L. J., Liu, L., ... & Dong, Z. Y. (2023). CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy. Nature Communications, 14(1), 1247.

Zhang, Y., Zhang, L., Zheng, S., Li, M., Xu, C., Jia, D., ... & Zhuo, W. (2022). Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis. Gut Microbes, 14(1), 2038852.

Chen, M., Wu, C., Fu, Z., & Liu, S. (2022). ICAM1 promotes bone metastasis via integrin‐mediated TGF‐β/EMT signaling in triple‐negative breast cancer. Cancer Science, 113(11), 3751.

Hsieh, C. Y., Lin, C. C., Huang, Y. W., Chen, J. H., Tsou, Y. A., Chang, L. C., ... & Chang, W. C. (2022). Macrophage secretory IL-1β promotes docetaxel resistance in head and neck squamous carcinoma via SOD2/CAT-ICAM1 signaling. JCI insight, 7(23).

Taftaf, R., Liu, X., Singh, S., Jia, Y., Dashzeveg, N. K., Hoffmann, A. D., ... & Liu, H. (2021). ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer. Nature communications, 12(1), 4867.

Gönen, M. S., Alaylıoğlu, M., Durcan, E., Özdemir, Y., Şahin, S., Konukoğlu, D., ... & Dursun, E. (2021). Rapid and effective vitamin D supplementation may present better clinical outcomes in COVID-19 (SARS-CoV-2) patients by altering serum INOS1, IL1B, IFNg, cathelicidin-LL37, and ICAM1. Nutrients, 13(11), 4047.

Chen, X., Zhang, X., Su, C., & Huang, S. (2020). Long noncoding RNA HULC in acute ischemic stroke: Association with disease risk, severity, and recurrence‐free survival and relation with IL‐6, ICAM1, miR‐9, and miR‐195. Journal of clinical laboratory analysis, 34(11), e23500.

Lin, J. C., Tsai, J. T., Chao, T. Y., Ma, H. I., & Liu, W. H. (2019). Musashi-1 enhances glioblastoma migration by promoting ICAM1 translation. Neoplasia, 21(5), 459-468.

Zhang, Y., Willis-Owen, S. A., Spiegel, S., Lloyd, C. M., Moffatt, M. F., & Cookson, W. O. (2019). The ORMDL3 asthma gene regulates ICAM1 and has multiple effects on cellular inflammation. American journal of respiratory and critical care medicine, 199(4), 478-488.

Figenschau, S. L., Knutsen, E., Urbarova, I., Fenton, C., Elston, B., Perander, M., ... & Fenton, K. A. (2018). ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes. Scientific reports, 8(1), 11720.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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