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ID2 Matched Antibody Pair (584) (APMAB-584LY)

This antibody pair set can be used for detecting and quantifying protein level of human ID2.
See all ID2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-ID2 polyclonal antibody, 100 ug
Detection Antibody
Anti-ID2 Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]
Alternative Names
Inhibitor Of DNA Binding 2
Entrez Gene ID
3398
UniProt ID
Q02363

Koppenhafer, S. L., Goss, K. L., Voigt, E., Croushore, E., Terry, W. W., Ostergaard, J., ... & Gordon, D. J. (2022). Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma. Oncogene, 41(20), 2873-2884.

Liu, F., Chen, S., Yu, Y., Huang, C., Chen, H., Wang, L., ... & Ye, Y. (2022). Inhibitor of DNA binding 2 knockdown inhibits the growth and liver metastasis of colorectal cancer. Gene, 819, 146240.

Yun, T., Ko, H. R., Jo, D. G., Park, K. W., Cho, S. W., Kim, J., & Ahn, J. Y. (2021). Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin. Cell Death Discovery, 7(1), 257.

Kim, H. R., Moon, J. H., Lee, J. H., & Lim, Y. C. (2021). Inhibitor of DNA binding 2 (ID2): a novel marker for lymph node metastasis in head and neck squamous cell carcinoma. Annals of Surgical Oncology, 1-10.

Huang, Z. H., Feng, A. Y., Liu, J., Zhou, L., Zhou, B., & Yu, P. (2021). Inhibitor of DNA binding 2 accelerates nerve regeneration after sciatic nerve injury in mice. Neural Regeneration Research, 16(12), 2542.

Duffield, G. E., Han, S., Hou, T. Y., de la Iglesia, H. O., McDonald, K. A., Mecklenburg, K. L., & Robles-Murguia, M. (2020). Inhibitor of DNA binding 2 (Id2) Regulates Photic Entrainment Responses in Mice: Differential Responses of the Id2-/-Mouse Circadian System Are Dependent on Circadian Phase and on Duration and Intensity of Light. Journal of Biological Rhythms, 35(6), 555-575.

Zhou, Y., Huan, L., Wu, Y., Bao, C., Chen, B., Wang, L., ... & He, X. (2020). LncRNA ID2-AS1 suppresses tumor metastasis by activating the HDAC8/ID2 pathway in hepatocellular carcinoma. Cancer letters, 469, 399-409.

Huang, Z., Liu, J., Jin, J., Chen, Q., Shields, L. B., Zhang, Y. P., ... & Yu, P. (2019). Inhibitor of DNA binding 2 promotes axonal growth through upregulation of Neurogenin2. Experimental Neurology, 320, 112966.

Han, J., Seo, H., Choi, Y., Lee, C., Kim, M. I., Jeon, Y., ... & Ka, H. (2018). Expression and regulation of inhibitor of DNA binding proteins ID1, ID2, ID3, and ID4 at the maternal-conceptus interface in pigs. Theriogenology, 108, 46-55.

Wen, X. F., Chen, M., Wu, Y., Chen, M. N., Glogowska, A., Klonisch, T., & Zhang, G. J. (2018). Inhibitor of DNA binding 2 inhibits epithelial-mesenchymal transition via up-regulation of Notch3 in breast cancer. Translational Oncology, 11(5), 1259-1270.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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