Mouse Anti-GNRH2 Recombinant Antibody (CAP847) (V2LY-0226-LY247)

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Basic Information

Host Animal
Mouse
Clone
CAP847
Application
WB, ELISA, IF, IP, IHC-P
Immunogen
Amino acids 1-120 of human GnRH II.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, gelatin
Preservative
Sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Gonadotropin Releasing Hormone 2
Entrez Gene ID
UniProt ID
Function
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Biological Process
Reproduction Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Secreted

Sun, A., Yan, X., Sun, J., Tian, Z., Wang, W., & Hu, H. (2022). Presence of GnRH3 in sturgeon and the roles of GnRH1 and GnRH2 on the regulation of LH/FSH in mature female sterlet Acipenser ruthenus in vitro. General and Comparative Endocrinology, 323, 114026.

Kumari, P., Kumar, M., Sehgal, N., & Aggarwal, N. (2022). In silico analysis of kiss2, expression studies and protein–protein interaction with gonadotropin-releasing hormone 2 (GnRH2) and luteinizing hormone beta (LHβ) in Heteropneustes fossilis. Journal of Biomolecular Structure and Dynamics, 40(10), 4543-4557.

Marvel, M., Levavi-Sivan, B., Wong, T. T., Zmora, N., & Zohar, Y. (2021). Gnrh2 maintains reproduction in fasting zebrafish through dynamic neuronal projection changes and regulation of gonadotropin synthesis, oogenesis, and reproductive behaviors. Scientific Reports, 11(1), 1-16.

Yuan, D., Wang, B., Tang, T., Lei, L., Zhou, C., Li, Z., & Li, L. (2021). Characterization and evaluation of the tissue distribution of CRH, apelin, and GnRH2 reveal responses to feeding states in Schizothorax davidi. Fish Physiology and Biochemistry, 47, 421-438.

Feng, W., Wang, Z., Feng, D., Zhu, Y., Zhang, K., & Huang, W. (2020). The effects of common variants in MDM2 and GNRH2 genes on the risk and survival of osteosarcoma in Han populations from Northwest China. Scientific Reports, 10(1), 15939.

Wang, W., Chen, J., Fang, Y., Wang, B., Zou, Q., Wang, L., ... & Wang, K. (2019). Identification of gnrh2 and gnrh3 and their expression during brood pouch growth and short-term benzo (a) pyrene exposure in lined seahorse (Hippocampus erectus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 225, 108579.

Marvel, M. M., Spicer, O. S., Wong, T. T., Zmora, N., & Zohar, Y. (2019). Knockout of Gnrh2 in zebrafish (Danio rerio) reveals its roles in regulating feeding behavior and oocyte quality. General and Comparative Endocrinology, 280, 15-23.

Ding, H., Liu, M., Zhou, C., You, X., Suo, Z., Zhang, C., & Xu, D. (2019). Expression and regulation of GnRHR2 gene and testosterone secretion mediated by GnRH2 and GnRHR2 within porcine testes. The Journal of Steroid Biochemistry and Molecular Biology, 190, 161-172.

Feng, K., Luo, H., Hou, M., Li, Y., Chen, J., Zhu, Z., & Hu, W. (2018). Alternative splicing of GnRH2 and GnRH2-associated peptide plays roles in gonadal differentiation of the rice field eel, Monopterus albus. General and Comparative Endocrinology, 267, 9-17.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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