Mouse Gdf15 ELISA Kit (V2LY-0626-LY578)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099).
It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886).
On hepatocytes, inhibits growth hormone signaling (By similarity).
BMP signaling pathway Source: GO_Central
Cell-cell signaling Source: ProtInc
Glial cell-derived neurotrophic factor receptor signaling pathway Source: UniProtKB
Negative regulation of growth hormone receptor signaling pathway Source: UniProtKB
Negative regulation of multicellular organism growth Source: UniProtKB
Positive regulation of MAPK cascade Source: UniProtKB
Positive regulation of myoblast fusion Source: Ensembl
Positive regulation of pathway-restricted SMAD protein phosphorylation Source: GO_Central
Positive regulation of protein kinase B signaling Source: UniProtKB
Reduction of food intake in response to dietary excess Source: UniProtKB
Signal transduction Source: ProtInc
SMAD protein signal transduction Source: UniProtKB
Transforming growth factor beta receptor signaling pathway Source: ProtInc
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human GDF15 ELISA Kit (CAT#: V2LY-0626-LY211)
Human Recombinant GDF15 protein, Biotin Conjugated, AVI & His Tag (CAT#: V2LY-0526-LY4281)
Human Recombinant GDF15 protein, hFc Tag (CAT#: V2LY-0526-LY4282)
Human Recombinant GDF15 protein, hFc Tag-1 (CAT#: V2LY-0526-LY4283)
Human Recombinant GDF15 protein, His Tag (CAT#: V2LY-0526-LY4284)
Human Recombinant GDF15 (Mature Form) protein, His Tag (CAT#: V2LY-0526-LY4285)
Mouse Recombinant GDF15 protein, His Tag (CAT#: V2LY-0526-LY8354)
Rabbit Recombinant GDF15 protein, hFc Tag (CAT#: V2LY-0526-LY9125)
Related Products
Mouse Anti-GDF15 Recombinant Antibody (23G10.F8) (CAT#: CBMAB-G2708-LY)
Rat Anti-GDF15 Recombinant Antibody (CBLG1-826) (CAT#: V2LY-1225-LY986)
Mouse Anti-GDF15 (N-terminus) Recombinant Antibody (CBFYH-0302) (CAT#: CBMAB-H1173-FY)
Human GDF15 ELISA Kit (CAT#: V2LY-0626-LY211)
Mouse Recombinant GDF15 protein, His Tag (CAT#: V2LY-0526-LY8354)
Rabbit Anti-GDF15 Recombinant Antibody (CBFYM-1096) (CAT#: CBMAB-M1251-FY)
Mouse Anti-GDF15 Recombinant Antibody (CBWJN-0298) (CAT#: V2LY-1225-LY987)
Rat Anti-GDF15 Recombinant Antibody (6D12.H10.E4) (CAT#: CBMAB-G2711-LY)
Mouse Anti-GDF15 (AA 197-308) Recombinant Antibody (CBFYH-0303) (CAT#: CBMAB-H1174-FY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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