Mouse Igfals ELISA Kit (V2LY-0626-LY2432)

Name: Mouse Igfals ELISA Kit
SKU: V2LY-0626-LY2432
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.55 ng/mL

Detection Range

1-400 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Mouse

Assay Type

Sandwich

Reactivity

Mouse

Assay Time

1.5 h

Molecule Mass

67.0 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

Insulin Like Growth Factor Binding Protein Acid Labile Subunit

Function

Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

Biological Process

Cell adhesion Source: UniProtKB-KW
Signal transduction Source: ProtInc

Cellular Location

Extracellular space

Involvement in disease

Acid-labile subunit deficiency (ACLSD):
A disorder characterized by severely reduced serum IGF-I and IGFBP-3 concentrations and mild growth retardation. Pubertal delay in boys and insulin insensitivity are common findings.

Franzoni, A., Baldan, F., Passon, N., Mio, C., Driul, D., Cogo, P., ... & Damante, G. (2023). Novel IGFALS mutations with predicted pathogenetic effects by the analysis of AlphaFold structure. Endocrine, 79(2), 292-295.

Genç, R., & Sönmez, Z. (2023). IGFALS Gene Polymorphisms in Simmental Breed Cattle. Turkish Journal of Agriculture-Food Science and Technology, 11(4), 846-850.

Bayraktar, M., & Shoshin, O. (2022). Estimate of the Association of IGF-I and IGFALS Genes with Growth Traits in Hamdani Sheep. Brazilian Archives of Biology and Technology, 64.

Zhang, Y. Y., Jing, C. A. O., Xiao-Tong, C. H. E. N., Jun-Hui, C. H. E. N., & Zheng, Y. B. (2021). Liver tissue-specific genes Igfals, Cyp3a4, Slc22a1 and Cyp2e1 may be associated with poor prognosis of liver cancer. Acta Academiae Medicinae Sinicae, 371-381.

Xu, G., Deng, F., Zuo, Q., Liu, L., Dou, K., Cheng, Z., ... & Zhu, Y. (2021). Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation. Cellular & Molecular Immunology, 18(6), 1587-1589.

Fadel, I. M., Ragab, M. H., Eid, O. M., Helmy, N. A., El-Bassyouni, H. T., & Mazen, I. (2021). IGF1R, IGFALS, and IGFBP3 gene copy number variations in a group of non-syndromic Egyptian short children. Journal of Genetic Engineering and Biotechnology, 19(1), 1-7.

Kumar, A., Jain, V., Chowdhury, M. R., Kumar, M., Kaur, P., & Kabra, M. (2020). Pathogenic/likely pathogenic variants in the SHOX, GHR and IGFALS genes among Indian children with idiopathic short stature. Journal of Pediatric Endocrinology and Metabolism, 33(1), 79-88.

Alizadeh, F., Moradian, F., & Farhadi, A. (2020). Association of allelic polymorphisms of IGFALS gene with growth traits in Makouei and Ghezel sheep breeds. Tropical Animal Health and Production, 52, 3027-3034.

Poyrazoğlu, Ş., Hwa, V., Baş, F., Dauber, A., Rosenfeld, R., & Darendeliler, F. (2019). A novel homozygous mutation of the acid-labile subunit (IGFALS) gene in a male adolescent. Journal of Clinical Research in Pediatric Endocrinology, 11(4), 432.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Igfals ELISA Kit (CAT#: V2LY-0626-LY2390)

Related Products

Rat Igfals ELISA Kit (CAT#: V2LY-0626-LY2390)

Rat Anti-IGFALS Recombinant Antibody (4K23) (CAT#: CBMAB-A4463-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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