Mouse Npr3 ELISA Kit (V2LY-0626-LY1508)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0095 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
59.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Natriuretic Peptide Receptor 3
Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Biological Process
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathwayIEA:Ensembl
Negative regulation of adenylate cyclase activityIEA:Ensembl
Negative regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab
Negative regulation of smooth muscle cell proliferationIEA:Ensembl
Osteoclast proliferationISS:UniProtKB
Pancreatic juice secretionIEA:Ensembl
Phosphatidylinositol-mediated signalingIEA:Ensembl
Phospholipase C-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Positive regulation of nitric-oxide synthase activityISS:BHF-UCL
Positive regulation of urine volumeISS:UniProtKB
Regulation of blood pressureISS:UniProtKB
Regulation of osteoblast proliferationISS:UniProtKB
Skeletal system developmentISS:UniProtKB
VasodilationIEA:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 27-481
Helical: 482-504
Cytoplasmic: 505-541

Cronjé, H. T., Karhunen, V., Hovingh, G. K., Coppieters, K., Lagerstedt, J. O., Nyberg, M., & Gill, D. (2023). Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study. BMC medicine, 21(1), 1-11.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human NPR3 ELISA Kit (CAT#: V2LY-0626-LY3665)

Cattle NPR3 ELISA Kit (CAT#: V2LY-0626-LY441)

Related Products

Human NPR3 ELISA Kit (CAT#: V2LY-0626-LY3665)

Cattle NPR3 ELISA Kit (CAT#: V2LY-0626-LY441)

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Mouse Anti-NPR3 Recombinant Antibody (11B6) (CAT#: CBMAB-N3247-WJ)

Mouse Anti-NPR3 Recombinant Antibody (2B12) (CAT#: CBMAB-N3251-WJ)

Mouse Anti-NPR3 Recombinant Antibody (4H1) (CAT#: CBMAB-N3255-WJ)

Mouse Anti-NPR3 Recombinant Antibody (2G2) (CAT#: CBMAB-N3252-WJ)

Mouse Anti-NPR3 Recombinant Antibody (11A6) (CAT#: CBMAB-N3245-WJ)

Mouse Anti-NPR3 Recombinant Antibody (CBWJN-0276) (CAT#: CBMAB-N3250-WJ)

Mouse Anti-NPR3 Recombinant Antibody (11B5) (CAT#: CBMAB-N3246-WJ)

Isotype control

For research use only. Not intended for any clinical use.

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