Mouse Recombinant OPCML protein, His Tag (V2LY-0526-LY8725)

Go to compare Compare Online Inquiry
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host
HEK293 Cells
Protein Species
Mouse
Tag
His Tag
Protein Construction
This product is Mouse Recombinant OPCML protein, His Tag consist of Amino Acid: 5-313 and predicts a molecular mass of 32.7 kDa.
Molecule Mass
32.7 kDa
Sequence
Amino Acid: 5-313
Species
Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Opioid Binding Protein/Cell Adhesion Molecule Like
Function
Binds opioids in the presence of acidic lipids; probably involved in cell contact.
Biological Process
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Neuron recognitionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
Involvement in disease
Ovarian cancer (OC):
The term ovarian cancer defines malignancies originating from ovarian tissue. Although many histologic types of ovarian tumors have been described, epithelial ovarian carcinoma is the most common form. Ovarian cancers are often asymptomatic and the recognized signs and symptoms, even of late-stage disease, are vague. Consequently, most patients are diagnosed with advanced disease.

Khamko, R., Wasenang, W., Daduang, J., Settasatian, C., & Limpaiboon, T. (2022). Combined OPCML and AXL expression as a prognostic marker and OPCML enhances AXL inhibitor in cholangiocarcinoma. in vivo, 36(3), 1168-1177.

Zhang, Y., Sun, X., Zhang, Y., Kang, Z., Cai, L., Ding, J., ... & Hu, G. (2022). GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients. Pharmacological Research, 184, 106459.

Shao, Y., Kong, J., Xu, H., Wu, X., Cao, Y., Li, W., ... & Wu, J. (2021). OPCML methylation and the risk of ovarian cancer: a meta and bioinformatics analysis. Frontiers in Cell and Developmental Biology, 9, 570898.

Antony, J., Zanini, E., Birtley, J. R., Gabra, H., & Recchi, C. (2021). Emerging roles for the GPI-anchored tumor suppressor OPCML in cancers. Cancer Gene Therapy, 28(1), 18-26.

Lian, B., Li, H., Liu, Y., Chai, D., Gao, Y., Zhang, Y., ... & Li, J. (2021). Expression and promoter methylation status of OPCML and its functions in the inhibition of cell proliferation, migration, and invasion in breast cancer. Breast Cancer, 28, 448-458.

Fang, X., Dong, Y., Yang, R., & Wei, L. (2020). LINC00619 restricts gastric cancer progression by preventing microRNA-224-5p-mediated inhibition of OPCML. Archives of biochemistry and biophysics, 689, 108390.

Simovic, I., Castaño-Rodríguez, N., & Kaakoush, N. O. (2019). OPCML: a promising biomarker and therapeutic avenue. Trends in Cancer, 5(8), 463-466.

Zhang, Z., Ye, M., Li, Q., You, Y., Yu, H., Ma, Y., ... & Zhang, D. (2019). The schizophrenia susceptibility gene OPCML regulates spine maturation and cognitive behaviors through Eph-Cofilin signaling. Cell Reports, 29(1), 49-61.

Wasenang, W., Chaiyarit, P., Proungvitaya, S., & Limpaiboon, T. (2019). Serum cell-free DNA methylation of OPCML and HOXD9 as a biomarker that may aid in differential diagnosis between cholangiocarcinoma and other biliary diseases. Clinical Epigenetics, 11, 1-10.

Birtley, J. R., Alomary, M., Zanini, E., Antony, J., Maben, Z., Weaver, G. C., ... & Gabra, H. (2019). Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions. Nature communications, 10(1), 3134.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Recombinant OPCML protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.