Mouse Recombinant SELL protein, His & hFc Tag (V2LY-0526-LY8632)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Mouse
Tag
His & hFc Tag
Protein Construction
This product is Mouse Recombinant SELL protein, His & hFc Tag consist of Amino Acid: 1-332 and predicts a molecular mass of 61 kDa.
Molecule Mass
61 kDa
Sequence
Amino Acid: 1-332
Species
Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>90% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile Tirs, NaCl, Glycerol
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Selectin L
Alternative Names
Selectin L; Leukocyte-Endothelial Cell Adhesion Molecule 1; CD62 Antigen-Like Family Member L; Leukocyte Surface Antigen Leu-8; Lymphocyte Adhesion Molecule 1; Lymph Node Homing Receptor; Gp90-MEL; LECAM1; LYAM1; LNHR; TQ1;
Function
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641).
Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
Biological Process
Biological Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukocyte cell-cell adhesionManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process leukocyte tethering or rollingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 39-332
Helical: 333-355
Cytoplasmic: 356-372
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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