Mouse Recombinant SERPINF1 protein, His Tag (V2LY-0526-LY8766)

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Datasheet
SDS
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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Mouse
Tag
His Tag
Protein Construction
This product is Mouse Recombinant SERPINF1 protein, His Tag consist of Amino Acid: 1-417 and predicts a molecular mass of 45.8 kDa.
Molecule Mass
45.8 kDa
Sequence
Amino Acid: 1-417
Species
Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-MALS(Routinely tested).
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Twelve months from date of receipt at -20°C to -70°C in lyophilized form and 3 months at -70°C under sterile conditions after reconstitution. Protect from prolonged exposure to light and avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Serpin Family F Member 1
Function
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Biological Process
Biological Process agingIEA:Ensembl
Biological Process cellular response to cobalt ionIEA:Ensembl
Biological Process cellular response to dexamethasone stimulusIEA:Ensembl
Biological Process cellular response to glucose stimulusIEA:Ensembl
Biological Process cellular response to retinoic acidIEA:Ensembl
Biological Process epithelial cell proliferation involved in prostate gland developmentIEA:Ensembl
Biological Process kidney developmentIEA:Ensembl
Biological Process negative regulation of angiogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of endothelial cell migrationIEA:Ensembl
Biological Process negative regulation of epithelial cell proliferation involved in prostate gland developmentIEA:Ensembl
Biological Process negative regulation of gene expressionIEA:Ensembl
Biological Process negative regulation of inflammatory responseIEA:Ensembl
Biological Process negative regulation of neuron deathIEA:Ensembl
Biological Process ovulation cycleIEA:Ensembl
Biological Process positive regulation of neurogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of neuron projection developmentIEA:Ensembl
Biological Process response to acidic pHIEA:Ensembl
Biological Process response to arsenic-containing substanceIEA:Ensembl
Biological Process response to peptideIEA:Ensembl
Biological Process retina development in camera-type eyeIEA:Ensembl
Biological Process short-term memoryIEA:Ensembl
Cellular Location
Secreted
Melanosome
Enriched in stage I melanosomes.
Involvement in disease
Osteogenesis imperfecta 6 (OI6):
A form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI6 is a severe, autosomal recessive form compatible with OI type III in the Sillence classification.
PTM
The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity.
N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant SERPINF1 protein, His Tag (CAT#: V2LY-0526-LY6101)

Rat Recombinant SERPINF1 protein, His Tag (CAT#: V2LY-0526-LY9553)

SERPINF1 Matched Antibody Pair (1073) (CAT#: APMAB-1073LY)

Antibody Pairs

SERPINF1 Matched Antibody Pair (1073) (CAT#: APMAB-1073LY)

Related Products

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SERPINF1 Matched Antibody Pair (1073) (CAT#: APMAB-1073LY)

Rat Recombinant SERPINF1 protein, His Tag (CAT#: V2LY-0526-LY9553)

Mouse Anti-SERPINF1 Recombinant Antibody (CBXS-3924) (CAT#: CBMAB-S0165-CQ)

Mouse Anti-SERPINF1 Recombinant Antibody (CBXS-0257) (CAT#: CBMAB-S3234-CQ)

Mouse Anti-SERPINF1 Recombinant Antibody (1C4) (CAT#: CBMAB-0820CQ)

Mouse Anti-SERPINF1 Recombinant Antibody (CBXS-0255) (CAT#: CBMAB-S3232-CQ)

Mouse Anti-SERPINF1 Recombinant Antibody (CBXS-1685) (CAT#: CBMAB-S4526-CQ)

Mouse Anti-SERPINF1 (AA 196-347) Recombinant Antibody (CBXS-0254) (CAT#: CBMAB-S3231-CQ)

Mouse Anti-SERPINF1 Recombinant Antibody (CBXS-0256) (CAT#: CBMAB-S3233-CQ)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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