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MS4A2 Matched Antibody Pair (756) (APMAB-756LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-MS4A2 polyclonal antibody, 100 ug
Detection Antibody
Anti-MS4A2 Mouse monoclonal, IgG2a antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
Alternative Names
Membrane Spanning 4-Domains A2; Fc Fragment Of IgE, High Affinity I, Receptor For; Beta Polypeptide; Membrane-Spanning 4-Domains Subfamily A Member 2; IgE Fc Receptor Subunit Beta; FCER1B; FcERI; IGER; APY; High Affinity Immunoglobulin Epsilon Receptor Beta-Subunit (FcERI) (IgE Fc Receptor, Beta-Subunit) (Fc Epsilon Receptor I Beta-Chain); Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment Of IgE, High Affinity I, Receptor For; Beta Polypeptide); High Affinity Immunoglobulin Epsilon Receptor Subunit Beta;
Entrez Gene ID
2206
UniProt ID
Q01362
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For research use only. Not intended for any clinical use.

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