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NADK Matched Antibody Pair (776) (APMAB-776LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-NADK monoclonal antibody, 100 ug
Detection Antibody
Anti-NADK Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008]
Alternative Names
NAD Kinase; Poly(P)/ATP NAD Kinase; EC 2.7.1.23; DJ283E3.1; EC 2.7.1;
Entrez Gene ID
65220
UniProt ID
O95544
More Infomation

Oka, S. I., Titus, A. S., Zablocki, D., & Sadoshima, J. (2023). Molecular properties and regulation of NAD+ kinase (NADK). Redox Biology, 59, 102561.

Zhang, R., & Zhang, K. (2023). Mitochondrial NAD kinase in health and disease. Redox Biology, 60, 102613.

Du, J., Estrella, M., Solorio-Kirpichyan, K., Jeffrey, P. D., & Korennykh, A. (2022). Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proceedings of the National Academy of Sciences, 119(26), e2200923119.

Kim, H., Fu, Z., Yang, Z., Song, Z., Yumnamcha, T., Sun, S., ... & Zhang, K. (2022). The mitochondrial NAD kinase functions as a major metabolic regulator upon increased energy demand. Molecular Metabolism, 64, 101562.

Xu, M., Ding, L., Liang, J., Yang, X., Liu, Y., Wang, Y., ... & Huang, X. (2021). NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis. Cell Reports, 37(13).

Wang, X., Li, B. B., Ma, T. T., Sun, L. Y., Tai, L., Hu, C. H., ... & Chen, K. M. (2020). The NAD kinase OsNADK1 affects the intracellular redox balance and enhances the tolerance of rice to drought. BMC plant biology, 20(1), 1-19.

Rabani, R., Cossette, C., Graham, F., & Powell, W. S. (2020). Protein kinase C activates NAD kinase in human neutrophils. Free Radical Biology and Medicine, 161, 50-59.

Ishikawa, Y., & Kawai-Yamada, M. (2019). Physiological significance of NAD kinases in cyanobacteria. Frontiers in Plant Science, 10, 847.

Hoxhaj, G., Ben-Sahra, I., Lockwood, S. E., Timson, R. C., Byles, V., Henning, G. T., ... & Manning, B. D. (2019). Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase. Science, 363(6431), 1088-1092.

Tai, L., Li, B. B., Nie, X. M., Zhang, P. P., Hu, C. H., Zhang, L., ... & Chen, K. M. (2019). Calmodulin is the fundamental regulator of NADK-mediated NAD signaling in plants. Frontiers in Plant Science, 10, 681.

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For research use only. Not intended for any clinical use.

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