NEDD9 Matched Antibody Pair (785) (APMAB-785LY)

Name: NEDD9 Matched Antibody Pair (785)
SKU: APMAB-785LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-NEDD9 polyclonal antibody, 100 ug

Detection Antibody

Anti-NEDD9 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Alternative Names

Neural Precursor Cell Expressed, Developmentally Down-Regulated 9; Cas Scaffolding Protein Family Member 2; Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 9; Renal Carcinoma Antigen NY-REN-12; CAS-L; CASS2; HEF1; CASL; Crk-Associated Substrate Related Protein Cas-L; CRK-Associated Substrate-Related Protein;

Entrez Gene ID

4739

UniProt ID

Q14511

More Infomation

Hu, Z., Wei, F., Su, Y., Wang, Y., Shen, Y., Fang, Y., ... & Chen, Y. (2023). Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression. Signal Transduction and Targeted Therapy, 8(1), 11.

Deneka, A. Y., Nikonova, A. S., Lee, H. O., Kruger, W. D., & Golemis, E. A. (2022). NEDD9 sustains hexokinase expression to promote glycolysis. Oncogenesis, 11(1), 15.

Deneka, A. Y., Kopp, M. C., Nikonova, A. S., Gaponova, A. V., Kiseleva, A. A., Hensley, H. H., ... & Golemis, E. A. (2021). Nedd9 Restrains Autophagy to Limit Growth of Early Stage Non–Small Cell Lung Cancer. Cancer research, 81(13), 3717-3726.

Alba, G. A., Samokhin, A. O., Wang, R. S., Zhang, Y. Y., Wertheim, B. M., Arons, E., ... & Maron, B. A. (2021). NEDD9 is a novel and modifiable mediator of platelet–endothelial adhesion in the pulmonary circulation. American journal of respiratory and critical care medicine, 203(12), 1533-1545.

Hua, S., Feng, T., Yin, L., Wang, Q., & Shao, X. (2021). NEDD9 overexpression: Prognostic and guidance value in acute myeloid leukaemia. Journal of cellular and molecular medicine, 25(19), 9331-9339.

Samokhin, A. O., Hsu, S., Paul, B. Y., Waxman, A. B., Alba, G. A., Wertheim, B. M., ... & Maron, B. A. (2020). Circulating NEDD9 is increased in pulmonary arterial hypertension: a multicenter, retrospective analysis. The Journal of Heart and Lung Transplantation, 39(4), 289-299.

Meng, H., Wu, J., Huang, Q., Yang, X., Yang, K., Qiu, Y., ... & Qi, H. (2019). NEDD9 promotes invasion and migration of colorectal cancer cell line HCT116 via JNK/EMT. Oncology Letters, 18(4), 4022-4029.

Gu, Y., Lu, J., Chen, C., & Zheng, F. (2019). NEDD9 overexpression predicts poor prognosis in solid cancers: a meta-analysis. OncoTargets and therapy, 12, 4213.

Zhao, S., Min, P., Liu, L., Zhang, L., Zhang, Y., Wang, Y., ... & Gu, L. (2019). NEDD9 facilitates hypoxia-induced gastric cancer cell migration via MICAL1 related Rac1 activation. Frontiers in pharmacology, 10, 291.

Jurčić, P., Radulović, P., Balja, M. P., Milošević, M., & Krušlin, B. (2019). E‑cadherin and NEDD9 expression in primary colorectal cancer, metastatic lymph nodes and liver metastases. Oncology Letters, 17(3), 2881-2889.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

NEDD9 Matched Antibody Pair (784) (CAT#: APMAB-784LY)

Antibody Pairs

NEDD9 Matched Antibody Pair (784) (CAT#: APMAB-784LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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