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NMI Matched Antibody Pair (804) (APMAB-804LY)

This antibody pair set can be used for detecting and quantifying protein level of human NMI.
See all NMI antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-NMI polyclonal antibody, 100 ug
Detection Antibody
Anti-NMI Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]
Alternative Names
N-Myc And STAT Interactor; N-Myc (And STAT) Interactor; N-Myc-Interactor; NMI;
Entrez Gene ID
UniProt ID

Hu, H., Li, B., Chen, H., Fan, G., Ye, Z., Ji, S., ... & Qin, Y. (2024). NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3‐IFIT3 axis. Molecular Carcinogenesis, 63(2), 195-208.

Feng, L., Li, W., Li, X., Li, X., Ran, Y., Yang, X., ... & Li, H. (2023). N‐MYC‐interacting protein enhances type II interferon signaling by inhibiting STAT1 sumoylation. The FASEB Journal, 37(12), e23281.

Li, L., Chen, S. N., Li, N., & Nie, P. (2022). Molecular characterization and transcriptional conservation of N-myc-interactor, Nmi, by type I and type II IFNs in mandarin fish Siniperca chuatsi. Developmental & Comparative Immunology, 130, 104354.

Zhang, W., Zhou, H., Cen, M., Ouyang, W., Chen, J., Xia, L., ... & Xu, F. (2022). N-myc and STAT interactor is a novel biomarker of severity in community-acquired pneumonia: a prospective study. Respiratory Research, 23(1), 1-11.

Banday, M. M., Kumar, A., Vestal, G., Sethi, J., Patel, K. N., O'Neill, E. B., ... & Sharma, N. S. (2021). N-myc-interactor mediates microbiome induced epithelial to mesenchymal transition and is associated with chronic lung allograft dysfunction. The Journal of Heart and Lung Transplantation, 40(6), 447-457.

Wu, S., Li, X., Chai, H., Feng, L., Li, W., & Li, H. (2021). Downregulation of N-myc interactor promotes cervical cancer cells growth by activating Stat3 signaling. Cell Biochemistry and Biophysics, 79, 103-111.

Ji, D., Feng, Y., Peng, W., Li, J., Gu, Q. O., Zhang, Z., ... & Sun, Y. (2020). NMI promotes cell proliferation through TGFβ/Smad pathway by upregulating STAT1 in colorectal cancer. Journal of Cellular Physiology, 235(1), 429-441.

Choi, J. E., Hyun, C. L., Jin, M. S., Lee, K. M., Moon, J. H., & Ryu, H. S. (2020). Downregulation of N-myc and STAT interactor protein predicts aggressive tumor behavior and poor prognosis in invasive ductal carcinoma. Journal of Breast Cancer, 23(1), 36-46.

Xia, J., Blank, M. L., Zhou, L. J., Wu, S. Z., Peng, H. J., & Boyle, J. P. (2020). Strain-specific disruption of interferon-stimulated N-myc and STAT interactor (NMI) function by Toxoplasma gondii type I ROP18 in human cells. Parasitology, 147(13), 1433-1442.

Xiong, L., Du, Y., Zhou, T., Du, B., Visalath, P., Lin, L., ... & Cai, W. (2019). N‐myc and STAT interactor correlates with severity and prognosis in acute‐on‐chronic liver failure of hepatitis B virus. Journal of Gastroenterology and Hepatology, 34(10), 1800-1808.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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