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NNMT Matched Antibody Pair (805) (APMAB-805LY)

This antibody pair set can be used for detecting and quantifying protein level of human NNMT.
See all NNMT antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-NNMT polyclonal antibody, 100 ug
Detection Antibody
Anti-NNMT Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]
Alternative Names
Nicotinamide N-Methyltransferase; EC 2.1.1.1;
Entrez Gene ID
4837
UniProt ID
P40261

Wang, W., Yang, C., Wang, T., & Deng, H. (2022). Complex roles of nicotinamide N-methyltransferase in cancer progression. Cell Death & Disease, 13(3), 267.

Takahashi, R., Kanda, T., Komatsu, M., Itoh, T., Minakuchi, H., Urai, H., ... & Itoh, H. (2022). The significance of NAD+ metabolites and nicotinamide N-methyltransferase in chronic kidney disease. Scientific reports, 12(1), 6398.

Parsons, R. B., & Facey, P. D. (2021). Nicotinamide N-methyltransferase: an emerging protagonist in cancer macro (r) evolution. Biomolecules, 11(10), 1418.

Roberti, A., Fernández, A. F., & Fraga, M. F. (2021). Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation. Molecular Metabolism, 45, 101165.

Campagna, R., Mateuszuk, Ł., Wojnar-Lason, K., Kaczara, P., Tworzydło, A., Kij, A., ... & Chlopicki, S. (2021). Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1868(10), 119082.

Gao, Y., Martin, N. I., & van Haren, M. J. (2021). Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target. Drug Discovery Today, 26(11), 2699-2706.

Campagna, R., Pozzi, V., Sartini, D., Salvolini, E., Brisigotti, V., Molinelli, E., ... & Emanuelli, M. (2021). Beyond Nicotinamide Metabolism: Potential Role of Nicotinamide N-Methyltransferase as a Biomarker in Skin Cancers. Cancers, 13(19), 4943.

Togni, L., Mascitti, M., Sartini, D., Campagna, R., Pozzi, V., Salvolini, E., ... & Emanuelli, M. (2021). Nicotinamide N-Methyltransferase in head and neck tumors: A comprehensive review. Biomolecules, 11(11), 1594.

Ramsden, D. B., Waring, R. H., Parsons, R. B., Barlow, D. J., & Williams, A. C. (2020). Nicotinamide N-methyltransferase: genomic connection to disease. International Journal of Tryptophan Research, 13, 1178646920919770.

Gao, Y., Van Haren, M. J., Moret, E. E., Rood, J. J., Sartini, D., Salvucci, A., ... & Martin, N. I. (2019). Bisubstrate inhibitors of nicotinamide N-methyltransferase (NNMT) with enhanced activity. Journal of medicinal chemistry, 62(14), 6597-6614.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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