NNMT Matched Antibody Pair (805) (APMAB-805LY)

Name: NNMT Matched Antibody Pair (805)
SKU: APMAB-805LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-NNMT polyclonal antibody, 100 ug

Detection Antibody

Anti-NNMT Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]

Alternative Names

Nicotinamide N-Methyltransferase; EC 2.1.1.1;

Entrez Gene ID

4837

UniProt ID

P40261

More Infomation

Wang, W., Yang, C., Wang, T., & Deng, H. (2022). Complex roles of nicotinamide N-methyltransferase in cancer progression. Cell Death & Disease, 13(3), 267.

Takahashi, R., Kanda, T., Komatsu, M., Itoh, T., Minakuchi, H., Urai, H., ... & Itoh, H. (2022). The significance of NAD+ metabolites and nicotinamide N-methyltransferase in chronic kidney disease. Scientific reports, 12(1), 6398.

Parsons, R. B., & Facey, P. D. (2021). Nicotinamide N-methyltransferase: an emerging protagonist in cancer macro (r) evolution. Biomolecules, 11(10), 1418.

Roberti, A., Fernández, A. F., & Fraga, M. F. (2021). Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation. Molecular Metabolism, 45, 101165.

Campagna, R., Mateuszuk, Ł., Wojnar-Lason, K., Kaczara, P., Tworzydło, A., Kij, A., ... & Chlopicki, S. (2021). Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1868(10), 119082.

Gao, Y., Martin, N. I., & van Haren, M. J. (2021). Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target. Drug Discovery Today, 26(11), 2699-2706.

Campagna, R., Pozzi, V., Sartini, D., Salvolini, E., Brisigotti, V., Molinelli, E., ... & Emanuelli, M. (2021). Beyond Nicotinamide Metabolism: Potential Role of Nicotinamide N-Methyltransferase as a Biomarker in Skin Cancers. Cancers, 13(19), 4943.

Togni, L., Mascitti, M., Sartini, D., Campagna, R., Pozzi, V., Salvolini, E., ... & Emanuelli, M. (2021). Nicotinamide N-Methyltransferase in head and neck tumors: A comprehensive review. Biomolecules, 11(11), 1594.

Ramsden, D. B., Waring, R. H., Parsons, R. B., Barlow, D. J., & Williams, A. C. (2020). Nicotinamide N-methyltransferase: genomic connection to disease. International Journal of Tryptophan Research, 13, 1178646920919770.

Gao, Y., Van Haren, M. J., Moret, E. E., Rood, J. J., Sartini, D., Salvucci, A., ... & Martin, N. I. (2019). Bisubstrate inhibitors of nicotinamide N-methyltransferase (NNMT) with enhanced activity. Journal of medicinal chemistry, 62(14), 6597-6614.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Canine Recombinant NNMT, Active protein, GST Tag (CAT#: V2LY-0526-LY1299)

Human Recombinant NNMT, Active protein, GST Tag (CAT#: V2LY-0526-LY5812)

Human NNMT ELISA Kit (CAT#: V2LY-0626-LY3823)

Related Products

Canine Recombinant NNMT, Active protein, GST Tag (CAT#: V2LY-0526-LY1299)

Mouse Anti-NNMT Recombinant Antibody (1A1) (CAT#: CBMAB-N2841-WJ)

Human Recombinant NNMT, Active protein, GST Tag (CAT#: V2LY-0526-LY5812)

Human NNMT ELISA Kit (CAT#: V2LY-0626-LY3823)

Mouse Anti-NNMT Recombinant Antibody (G-4) (CAT#: CBMAB-N2847-WJ)

Mouse Anti-NNMT Recombinant Antibody (2F2) (CAT#: CBMAB-N2843-WJ)

Mouse Anti-NNMT Recombinant Antibody (2A3) (CAT#: CBMAB-N2842-WJ)

Mouse Anti-NNMT Recombinant Antibody (2G8) (CAT#: CBMAB-N2844-WJ)

Mouse Anti-NNMT Recombinant Antibody (CBWJN-1456) (CAT#: CBMAB-N2840-WJ)

Mouse Anti-NNMT Recombinant Antibody (3D8) (CAT#: CBMAB-N2846-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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