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Rabbit Anti-H1-0 Recombinant Antibody (CBNH-063) (V2LY-0226-LY2419)

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Basic Information

Host Animal
Rabbit
Clone
CBNH-063
Application
WB, IF, IHC-P
Immunogen
Synthetic peptide within human histone h10 (aa 1-50).
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
TBS, BSA, glycerol
Preservative
Sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
H1.0 linker histone
Entrez Gene ID
Human3005
Mouse14958
Rat24437
UniProt ID
HumanP07305
MouseP10922
RatP43278
Alternative Names
H10; H1.0; H1F0; H1FV
Function
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Biological Process
Chromosome condensation
Heterochromatin formation
Negative regulation of DNA recombination
Nucleosome assembly
Positive regulation of transcription regulatory region DNA binding
Cellular Location
Nucleus
Chromosome
Note: The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
PTM
Phosphorylated on Ser-17 in RNA edited version.
ADP-ribosylated on Ser-104 in response to DNA damage.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-H1-0 Recombinant Antibody (CBFYH-0564) (CAT#: V2LY-0226-LY2409)

Rabbit Anti-H1-0 Recombinant Antibody (
1C7) (CAT#: V2LY-0725-LY741)

Mouse Anti-H1-0 Recombinant Antibody (CBFYH-0565) (CAT#: CBMAB-H1451-FY)

Rabbit Anti-H1-0 Recombinant Antibody (CBFYH-3000) (CAT#: CBMAB-H1449-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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