Rabbit GSR ELISA Kit (V2LY-0626-LY375)

Name: Rabbit GSR ELISA Kit
SKU: V2LY-0626-LY375
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.027 ng/mL

Detection Range

0.05-100 ng/mL

Sample Type

Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue

Specificity

Rabbit

Assay Type

Sandwich

Reactivity

Rabbit

Assay Time

1.5 h

Components

Standard Solution: 0.5ml x1
Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard Diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop Solution: 6ml x1
Substrate Solution A: 6ml x1
Substrate Solution B: 6ml x1
Wash Buffer Concentrate (25x): 20ml x1
Biotinylated Antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

glutathione reductase

Function

Maintains high levels of reduced glutathione in the cytosol.

Biological Process

Cell redox homeostasis Source: GO_Central
Cellular response to oxidative stress Source: GO_Central
Glutathione metabolic process Source: GO_Central

Cellular Location

Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic: Cytoplasm

Involvement in disease

Hemolytic anemia due to glutathione reductase deficiency (HAGRD):
An autosomal recessive disease characterized by hemolytic anemia and impaired activity of glutathione reductase. Patients experience hemolytic anemia in response to oxidative stress or ingestion of fava beans.

Xu, C., Luo, M., Liu, X., Wei, T., Zhou, Z., Li, C., ... & Sui, H. (2023). MicroRNA-1298-5p in granulosa cells facilitates cell autophagy in polycystic ovary syndrome by suppressing glutathione-disulfide reductase. Cell and Tissue Research, 1-16.

Zhang, C., & Zhao, D. (2021). MicroRNA-362-5p promotes the proliferation and inhibits apoptosis of trophoblast cells via targeting glutathione-disulfide reductase. Bioengineered, 12(1), 2410-2419.

Johnson, F. D., Ferrarone, J., Liu, A., Brandstädter, C., Munuganti, R., Farnsworth, D., ... & Lockwood, W. W. (2021). A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1. bioRxiv, 2021-06.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Gsr ELISA Kit (CAT#: V2LY-0626-LY1365)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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