Rat Ccl6 ELISA Kit (V2LY-0626-LY2116)

Name: Rat Ccl6 ELISA Kit
SKU: V2LY-0626-LY2116
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.025 ng/mL

Detection Range

0.05-20 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Rat

Assay Type

Sandwich

Reactivity

Rat

Assay Time

1.5 h

Molecule Mass

12.7 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

chemokine (C-C motif) ligand 6

Function

CCL6(22-95) and CCL6(23-95) are potent chemoattractants.

Biological Process

Cell chemotaxis Source: MGI
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central

Cellular Location

Secreted

Li, F., Du, X., Lan, F., Li, N., Zhang, C., Zhu, C., ... & Shen, H. (2021). Eosinophilic inflammation promotes CCL6-dependent metastatic tumor growth. Science Advances, 7(22), eabb5943.

Li, X., Aishan, B., Yang, Y., Xie, Y., Lati, D., & Tuerxun, P. (2020). Chemokine (CC motif) Ligand 6 Aggravates Hypoxia Reoxygenation–induced Apoptosis in H9c2 Cells Through Enhancing the Expression of Insulin-like Growth Factor 2-Antisense. Journal of Cardiovascular Pharmacology, 76(5), 549-555.

Du, X., Li, F., Li, N., Shao, Z., Zhang, C., Huang, H., ... & Shen, H. (2020). Eosinophil-Derived Chemokine CCL6 Promote Allergic Airway Inflammation. In D91. EOSINOPHILS IN ASTHMA, PATHOPHYSIOLOGICAL AND CLINICAL IMPLICATIONS (pp. A7630-A7630). American Thoracic Society.

Du, X., Li, F., Shao, Z., Zhang, C., Li, W., Chen, Z., ... & Shen, H. (2019). CCL6 produced by eosinophils drives allergic airway inflammation in mice.

Zhang, C., Yi, W., Li, F., Du, X., Wang, H., Wu, P., ... & Shen, H. (2018). Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis. Cell research, 28(3), 323-335.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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