PGF

PGF is a growth factor found in placenta which is homologous to vascular endothelial growth factor.
Full Name
Placental Growth Factor
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Biological Process
Animal organ regenerationIEA:Ensembl
Cell differentiationIEA:UniProtKB-KW
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to hormone stimulusIEA:Ensembl
Female pregnancyIEA:Ensembl
Induction of positive chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of mast cell chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Response to hypoxiaManual Assertion Based On ExperimentIBA:GO_Central
Response to xenobiotic stimulusIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Sprouting angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
PTM
N-glycosylated.
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Anti-PGF antibodies

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Mouse Anti-PGF Recombinant Antibody (PLGF94) (CBMAB-P1575-YC)

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Target: PGF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PLGF94
Application*: E
Datasheet SDS

Mouse Anti-PGF Recombinant Antibody (PLGF/94) (CBMAB-P1574-YC)

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Target: PGF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PLGF/94
Application*: WB, E, FN
Datasheet SDS

Mouse Anti-PGF Recombinant Antibody (PLGF/93) (CBMAB-P1573-YC)

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Target: PGF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PLGF/93
Application*: E, FN
Datasheet SDS

Rat Anti-PGF Recombinant Antibody (9G33) (CBMAB-P1572-YC)

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Target: PGF
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 9G33
Application*: WB, B, N
Datasheet SDS

Rat Anti-PGF Recombinant Antibody (8F09) (CBMAB-P1571-YC)

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Target: PGF
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 8F09
Application*: WB, N
Datasheet SDS

Mouse Anti-PGF Recombinant Antibody (178/G10) (CBMAB-P1568-YC)

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Target: PGF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 178/G10
Application*: WB, E
Datasheet SDS

Rabbit Anti-PGF Recombinant Antibody (
1B6) (V2LY-0725-LY1157)

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Target: PGF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1B6
Application*: E, IH
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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