Rat Pgf ELISA Kit (V2LY-0626-LY985)

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Tested Data
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Basic Information

Sensitivity
0.00055 ng/mL
Detection Range
0.001-0.4 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
17.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Placental Growth Factor
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Biological Process
Animal organ regenerationIEA:Ensembl
Cell differentiationIEA:UniProtKB-KW
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to hormone stimulusIEA:Ensembl
Female pregnancyIEA:Ensembl
Induction of positive chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of mast cell chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Response to hypoxiaManual Assertion Based On ExperimentIBA:GO_Central
Response to xenobiotic stimulusIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Sprouting angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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