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Mouse Anti-PGF Recombinant Antibody (PLGF/94) (CBMAB-P1574-YC)

Provided herein is a Mouse monoclonal antibody against Human Placental Growth Factor. The antibody can be used for immunoassay techniques, such as WB, ELISA, FuncS.
See all PGF antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
PLGF/94
Antibody Isotype
IgG1, κ
Application
WB, ELISA, FuncS

Basic Information

Immunogen
Recombinant human PLGF protein
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Placental Growth Factor
Introduction
PGF is a growth factor found in placenta which is homologous to vascular endothelial growth factor.
Entrez Gene ID
5228
UniProt ID
P49763
Alternative Names
PGFL; PlGF-2; PIGF; SHGC-10760; D12S1900; PLGF
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Biological Process
Animal organ regenerationIEA:Ensembl
Cell differentiationIEA:UniProtKB-KW
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to hormone stimulusIEA:Ensembl
Female pregnancyIEA:Ensembl
Induction of positive chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of mast cell chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Response to hypoxiaManual Assertion Based On ExperimentIBA:GO_Central
Response to xenobiotic stimulusIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Sprouting angiogenesisManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Vascular endothelial growth factor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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