ABAT

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD
Full Name
4-Aminobutyrate Aminotransferase
Function
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
Biological Process
Behavioral response to cocaine
Gamma-aminobutyric acid catabolic process
Gamma-aminobutyric acid metabolic process
Neurotransmitter catabolic process
Cellular Location
Mitochondrion matrix
Involvement in disease
An enzymatic deficiency resulting in psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.
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Anti-ABAT antibodies

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Mouse Anti-ABAT Recombinant Antibody (V2-178890) (CBMAB-A0117-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-178890
Application*: IH, WB, IF
Datasheet SDS

Mouse Anti-ABAT Recombinant Antibody (V2-178889) (CBMAB-A0116-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-178889
Application*: IH, WB
Datasheet SDS

Mouse Anti-ABAT Recombinant Antibody (V2-178888) (CBMAB-A0115-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-178888
Application*: IH, WB
Datasheet SDS

Mouse Anti-ABAT Recombinant Antibody (V2-178886) (CBMAB-A0113-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178886
Application*: WB
Datasheet SDS

Mouse Anti-ABAT Recombinant Antibody (V2-178883) (CBMAB-A0110-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178883
Application*: P
Datasheet SDS

Mouse Anti-ABAT Recombinant Antibody (V2-178880) (CBMAB-A0107-YC)

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Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178880
Application*: IH, WB
Datasheet SDS

Mouse Abat ELISA Kit (V2LY-0626-LY1712)

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Target: Abat
Sensitivity: 0.096 ng/mL
Detection Range: 0.2-60 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Rabbit Anti-ABAT Recombinant Antibody (
5B6) (V2LY-0725-LY1098)

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Target: ABAT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 5B6
Application*: E, IH
Datasheet SDS

Rabbit Anti-ABAT Recombinant Antibody (V2-12485) (CBMAB-0975-CN)

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Target: ABAT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: V2-12485
Application*: F, P, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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