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ABAT

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD
Full Name
4-Aminobutyrate Aminotransferase
Function
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
Biological Process
Behavioral response to cocaine
Gamma-aminobutyric acid catabolic process
Gamma-aminobutyric acid metabolic process
Neurotransmitter catabolic process
Cellular Location
Mitochondrion matrix
Involvement in disease
An enzymatic deficiency resulting in psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.

Anti-ABAT antibodies

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Mouse Anti-ABAT Recombinant Antibody (V2-178883) (CBMAB-A0110-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178883
Application*: P

Mouse Anti-ABAT Recombinant Antibody (V2-178890) (CBMAB-A0117-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-178890
Application*: IH, WB, IF

Mouse Anti-ABAT Recombinant Antibody (V2-178880) (CBMAB-A0107-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178880
Application*: IH, WB

Mouse Anti-ABAT Recombinant Antibody (V2-178886) (CBMAB-A0113-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-178886
Application*: WB

Mouse Anti-ABAT Recombinant Antibody (V2-178888) (CBMAB-A0115-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-178888
Application*: IH, WB

Mouse Anti-ABAT Recombinant Antibody (V2-178889) (CBMAB-A0116-YC)

Datasheet SDS
Target: ABAT
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-178889
Application*: IH, WB

Rabbit Anti-ABAT Recombinant Antibody (V2-12485) (CBMAB-0975-CN)

Datasheet SDS
Target: ABAT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: V2-12485
Application*: F, P, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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