ADAM33

ADAM33 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involvi

Full Name

ADAM Metallopeptidase Domain 33

Biological Process

Proteolysis

Cellular Location

Membrane

Involvement in disease

Asthma (ASTHMA): The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with wheezing due to spasmodic contraction of the bronchi.

Topology

Extracellular: 30-701 aa
Helical: 702-722 aa
Cytoplasmic: 723-813 aa

PTM

The precursor is cleaved by a furin endopeptidase.

Anti-ADAM33 antibodies

Rat Anti-ADAM33 Recombinant Antibody (V2-179792) (CBMAB-A1154-YC)

Datasheet

SDS

Target: ADAM33

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: V2-179792

Application*: WB, IP

Mouse Anti-ADAM33 Recombinant Antibody (V2-179794) (CBMAB-A1156-YC)

Datasheet

SDS

Target: ADAM33

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-179794

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)