ADGRE1

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Full Name
Adhesion G Protein-Coupled Receptor E1
Function
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
Biological Process
Adaptive immune response
Adenylate cyclase-activating G protein-coupled receptor signaling pathway
Cell adhesion
Cell surface receptor signaling pathway
G protein-coupled receptor signaling pathway
Cellular Location
Cell membrane
Topology
Extracellular: 21-599 aa
Helical: 600-627 aa
Cytoplasmic: 628-634 aa
Helical: 635-656 aa
Extracellular: 657-666 aa
Helical: 667-690 aa
Cytoplasmic: 691-709 aa
Helical: 710-731 aa
Extracellular: 732-747 aa
Helical: 748-776 aa
Cytoplasmic: 777-794 aa
Helical: 795-814 aa
Extracellular: 815-829 aa
Helical: 830-852 aa
Cytoplasmic: 853-886 aa
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Anti-ADGRE1 antibodies

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Rat Anti-ADGRE1 Recombinant Antibody (V2-43340) (CBMAB-E0265-FY)

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Target: ADGRE1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: V2-43340
Application*: F, IH
Datasheet SDS

Hamster Anti-ADGRE1 Recombinant Antibody (V2-160731) (CBMAB-F0651-CQ)

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Target: ADGRE1
Host: Hamster
Antibody Isotype: IgG
Specificity: Human
Clone: V2-160731
Application*: F
Datasheet SDS

Rat Anti-ADGRE1 Recombinant Antibody (V2-160162) (CBMAB-F0010-CQ)

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Target: ADGRE1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: V2-160162
Application*: F, IH
Datasheet SDS

Rabbit Anti-ADGRE1 Recombinant Antibody (V2-160161) (CBMAB-F0009-CQ)

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Target: ADGRE1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: V2-160161
Application*: IH, P, W
Datasheet SDS

Rat Anti-ADGRE1 Recombinant Antibody (V2-160159) (CBMAB-F0007-CQ)

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Target: ADGRE1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: V2-160159
Application*: WB, F, IH, IF, IP, P, R, EM
Datasheet SDS

Rat Anti-ADGRE1 Recombinant Antibody (V2-160157) (CBMAB-F0005-CQ)

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Target: ADGRE1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: V2-160157
Application*: WB, F, IH, P
Datasheet SDS

Rat Anti-ADGRE1 Recombinant Antibody (V2-160156) (CBMAB-F0004-CQ)

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Target: ADGRE1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: V2-160156
Application*: F, IH, IC, MC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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