ANO1

Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Full Name
Anoctamin 1
Function
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Biological Process
Cation transport Source: UniProtKB
Cellular response to heat Source: UniProtKB
Cellular response to peptide Source: Ensembl
Chloride transmembrane transport Source: UniProtKB
Chloride transport Source: UniProtKB
Detection of temperature stimulus involved in sensory perception of pain Source: UniProtKB
Iodide transport Source: UniProtKB
Ion transmembrane transport Source: Reactome
Multicellular organism development Source: UniProtKB-KW
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: UniProtKB
Positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: UniProtKB
Transmembrane transport Source: GO_Central
Cellular Location
Cytoplasm; Cell membrane. Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors.
Topology
Cytoplasmic: 1-333 aa
Helical: 334-354 aa
Extracellular: 355-406 aa
Helical: 407-427 aa
Cytoplasmic: 428-519 aa
Helical: 520-540 aa
Extracellular: 541-568 aa
Helical: 569-589 aa
Cytoplasmic: 590-607 aa
Helical: 608-628 aa
Extracellular: 629-657 aa
Helical: 658-678 aa
Cytoplasmic: 679-725 aa
Helical: 726-746 aa
Helical: 747-767 aa
Cytoplasmic: 768-784 aa
Helical: 785-805 aa
Extracellular: 806-892 aa
Helical: 893-913 aa
Cytoplasmic: 914-986 aa
View more

Anti-ANO1 antibodies

+ Filters
Loading...

Mouse Anti-ANO1 Recombinant Antibody (DG1/1484) (CBMAB-MA012-YC)

Go to compareCompare
Target: ANO1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: DG1/1484
Application*: IH
Datasheet SDS

Mouse Anti-ANO1 Recombinant Antibody (SPM580) (CBMAB-D0016-YC)

Go to compareCompare
Target: ANO1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM580
Application*: FC, IF, IH
Datasheet SDS

Mouse Anti-ANO1 Recombinant Antibody (DG1/1484) (CBMAB-D0011-YC)

Go to compareCompare
Target: ANO1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: DG1/1484
Application*: P, IC, IF, FC
Datasheet SDS

Rabbit Anti-ANO1 Monoclonal Antibody (SP31) (CBMAB-R0093-FY)

Go to compareCompare
Target: ANO1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP31
Application*: IH
Datasheet SDS

Rabbit Anti-ANO1 Recombinant Antibody (D1M9Q) (CBMAB-CP2783-LY)

Go to compareCompare
Target: ANO1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1M9Q
Application*: WB, IP, IF (IC)
Datasheet SDS

Mouse Anti-ANO1 Recombinant Antibody (CBYJT-1038) (CBMAB-T0042-YJ)

Go to compareCompare
Target: ANO1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-1038
Application*: IH, MA
Datasheet SDS

Mouse Anti-ANO1 Recombinant Antibody (CBYJT-1034) (CBMAB-T0038-YJ)

Go to compareCompare
Target: ANO1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-1034
Application*: WB, IP, P, IF, E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.