APBA3

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]

Full Name

Amyloid Beta Precursor Protein Binding Family A Member 3

Function

May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.

Biological Process

Chemical synaptic transmission Source: GO_Central
In utero embryonic development Source: Ensembl
Negative regulation of catalytic activity Source: UniProtKB
Protein transport Source: UniProtKB-KW
Regulation of gene expression Source: Ensembl

Cellular Location

Perinuclear region

Anti-APBA3 antibodies

Mouse Anti-APBA3 Recombinant Antibody (CBFYM-0863) (CBMAB-M1010-FY)

Datasheet

SDS

Target: APBA3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: CBFYM-0863

Application*: WB, IP, IF, E

Mouse Anti-APBA3 Recombinant Antibody (H-6) (CBMAB-X0001-YC)

Datasheet

SDS

Target: APBA3

Host: Mouse

Antibody Isotype: IgM, κ

Specificity: Human, Mouse, Rat

Clone: H-6

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)