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ATG2A

Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.

Full Name

Autophagy Related 2A

Function

Involved in autophagosome assembly, regulating the size of nascent autophagosomes (PubMed:28561066).
Also regulates lipid droplets morphology and distribution within the cell (PubMed:22219374, PubMed:28561066).
Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion (By similarity).

Biological Process

Autophagosome assembly Source: UniProtKB
Autophagy of mitochondrion Source: GO_Central
Late nucleophagy Source: GO_Central
Piecemeal microautophagy of the nucleus Source: GO_Central
Reticulophagy Source: GO_Central

Cellular Location

Endoplasmic reticulum membrane; Preautophagosomal structure membrane; Lipid droplet

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Anti-ATG2A antibodies

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Mouse Atg2a ELISA Kit (V2LY-0626-LY3298)

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Target: Atg2a

Sensitivity: 0.0052 ng/mL

Detection Range: 0.01-3 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Mouse

Assay Type: Sandwich

Reactivity: Mouse

Mouse Anti-ATG2A Recombinant Antibody (CBT4830) (V2LY-0625-LY639)

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Target: ATG2A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT4830

Application*: IC, F

Mouse Anti-ATG2A Recombinant Antibody (CBT4798) (V2LY-0625-LY638)

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Target: ATG2A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT4798

Application*: IC, F

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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