ATG4A

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, a
Full Name
Autophagy Related 4A Cysteine Peptidase
Function
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Biological Process
Autophagy Source: UniProtKB-KW
Protein transport Source: UniProtKB-KW
Proteolysis Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-ATG4A antibodies

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Mouse Anti-ATG4A Recombinant Antibody (808.66.25.69) (CBMAB-A3925-YC)

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Target: ATG4A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 808.66.25.69
Application*: IP, WB, P, IF, IC, FC
Datasheet SDS

Mouse Anti-ATG4A Recombinant Antibody (CBYC-A854) (CBMAB-A3927-YC)

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Target: ATG4A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBYC-A854
Application*: IC, IF, IP, WB
Datasheet SDS

Mouse Anti-ATG4A Recombinant Antibody (CBYC-A853) (CBMAB-A3926-YC)

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Target: ATG4A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYC-A853
Application*: E, IF, WB, FC
Datasheet SDS

Rabbit Anti-ATG4A Recombinant Antibody (13A159) (CBMAB-A3924-YC)

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Target: ATG4A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 13A159
Application*: IH, IP, WB
Datasheet SDS

Mouse Anti-ATG4A Recombinant Antibody (CBT3279) (V2LY-0625-LY1044)

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Target: ATG4A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3279
Application*: IC, F
Datasheet SDS

Mouse Anti-ATG4A Recombinant Antibody (CBT2240) (V2LY-0625-LY1043)

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Target: ATG4A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2240
Application*: F
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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