BCL2L14

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
Full Name
BCL2 Like 14
Function
Plays a role in apoptosis.
Biological Process
Apoptotic process Source: UniProtKB
Positive regulation of extrinsic apoptotic signaling pathway Source: UniProtKB
Regulation of apoptotic process Source: Reactome
Regulation of extrinsic apoptotic signaling pathway Source: GO_Central
Cellular Location
Cytoplasm
Isoform 1: Cytosol. Diffusely distributed throughout the cytosol.
Isoform 2: Endomembrane system. Predominantly localized to cytosolic organelles.
PTM
Phosphorylated by MELK, leading to inhibit its pro-apoptotic function.
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Anti-BCL2L14 antibodies

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Mouse Anti-BCL2L14 Recombinant Antibody (1D11) (CBMAB-A0738-LY)

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Target: BCL2L14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D11
Application*: WB, E
Datasheet SDS

Rabbit Anti-BCL2L14 Recombinant Antibody (CBYY-0425) (CBMAB-0427-YY)

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Target: BCL2L14
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBYY-0425
Application*: WB, P
Datasheet SDS

Mouse Anti-BCL2L14 Recombinant Antibody (CBYY-0423) (CBMAB-0425-YY)

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Target: BCL2L14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-0423
Application*: WB, E, IF, IP
Datasheet SDS

Mouse Anti-BCL2L14 Recombinant Antibody (CBYY-0422) (CBMAB-0424-YY)

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Target: BCL2L14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0422
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-BCL2L14 Recombinant Antibody (CBYY-0421) (CBMAB-0423-YY)

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Target: BCL2L14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0421
Application*: WB, E, IF, IP
Datasheet SDS

Mouse Anti-BCL2L14 Recombinant Antibody (CBYY-0420) (CBMAB-0422-YY)

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Target: BCL2L14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0420
Application*: E, IP, WB
Datasheet SDS

BCL2L14 Matched Antibody Pair (133) (APMAB-133LY)

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Target: BCL2L14
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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