BHLHA15

MIST1 is a basic helix-loop-helix (bHLH) protein that binds to the DNA target sequence CANNTG (E box) present in the promoter or enhancer region of numerous developmentally regulated genes.
Full Name
basic helix-loop-helix family, member a15
Function
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).
Biological Process
Calcium-mediated signaling Source: Ensembl
Cell-cell signaling Source: Ensembl
Cell maturation Source: Ensembl
Cellular response to glucose starvation Source: UniProtKB
Endoplasmic reticulum unfolded protein response Source: UniProtKB
Glucose homeostasis Source: Ensembl
Golgi organization Source: Ensembl
G protein-coupled receptor signaling pathway Source: Ensembl
Intracellular distribution of mitochondria Source: Ensembl
Mitochondrial calcium ion transmembrane transport Source: Ensembl
Negative regulation of myotube differentiation Source: UniProtKB
Neuron differentiation Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-BHLHA15 antibodies

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Mouse Anti-BHLHA15 Recombinant Antibody (1E7) (CBMAB-A0758-LY)

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Target: BHLHA15
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E7
Application*: WB, E
Datasheet SDS

Rabbit Anti-BHLHA15 Recombinant Antibody (CBFYM-0881) (CBMAB-M1028-FY)

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Target: BHLHA15
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBFYM-0881
Application*: WB, P
Datasheet SDS

Mouse Anti-BHLHA15 Recombinant Antibody (CBFYM-0880) (CBMAB-M1027-FY)

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Target: BHLHA15
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBFYM-0880
Application*: WB, IF, IP, P
Datasheet SDS

Mouse Anti-BHLHA15 Recombinant Antibody (CBYY-0532) (CBMAB-0535-YY)

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Target: BHLHA15
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-0532
Application*: WB, IF, IP, E, P
Datasheet SDS

Mouse Anti-BHLHA15 Recombinant Antibody (CBYY-0531) (CBMAB-0534-YY)

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Target: BHLHA15
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBYY-0531
Application*: WB, IF, IP, E, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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