BLVRA

Biliverdin reductases, such as BLVRA (EC 1.3.1.24), catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH (Komuro et al., 1996 [PubMed 8950184]).[supplied by OMIM
Full Name
biliverdin reductase A
Function
Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
Biological Process
Heme catabolic process Source: UniProtKB
Cellular Location
Cytoplasm
Involvement in disease
Hyperbiliverdinemia (HBLVD): A condition characterized by a green discoloration of the skin, urine, serum, and other bodily fluids. It is due to increased biliverdin resulting from inefficient conversion to bilirubin. Affected individuals appear to have symptoms only in the context of obstructive cholestasis and/or liver failure. In some cases, green jaundice can resolve after resolution of obstructive cholestasis.
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Anti-BLVRA antibodies

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Mouse Anti-BLVRA Recombinant Antibody (4G4-2B6) (CBMAB-A0802-LY)

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Target: BLVRA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4G4-2B6
Application*: WB, E
Datasheet SDS

Mouse Anti-BLVRA Recombinant Antibody (F1) (CBMAB-A0801-LY)

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Target: BLVRA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: F1
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-BLVRA Recombinant Antibody (CBYY-0628) (CBMAB-0631-YY)

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Target: BLVRA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-0628
Application*: WB, E, IP
Datasheet SDS

Human BLVRA ELISA Kit (V2LY-0626-LY3471)

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Target: BLVRA
Sensitivity: 0.023 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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