CBX8

CBX8 (Chromobox 8) is a Protein Coding gene. Diseases associated with CBX8 include Conversion Disorder. Among its related pathways are SUMOylation and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity and single-stranded RNA binding. An important paralog of this gene is CBX6.
Full Name
Chromobox 8
Function
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Biological Process
Cellular response to hydrogen peroxide Source: Ensembl
Histone ubiquitination Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of collagen biosynthetic process Source: Ensembl
Positive regulation of DNA repair Source: Ensembl
Cellular Location
Nucleus
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Anti-CBX8 antibodies

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Rabbit Anti-CBX8 Recombinant Antibody (D2O8C) (CBMAB-CP0155-LY)

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Target: CBX8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D2O8C
Application*: WB, IP
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (CBYY-C1042) (CBMAB-C2479-YY)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1042
Application*: E, WB, F
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (1C7) (CBMAB-C3763-LY)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 1C7
Application*: WB
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (121E2C) (CBMAB-C2574-LY)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 121E2C
Application*: F, WB
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (CBT4809) (V2LY-0625-LY941)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4809
Application*: WB, F
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (CBT3264) (V2LY-0625-LY939)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3264
Application*: F
Datasheet SDS

Rabbit Anti-CBX8 Recombinant Antibody (CBFYC-0906) (CBMAB-C0962-FY)

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Target: CBX8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-0906
Application*: WB, IF
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (CBFYC-0904) (CBMAB-C0960-FY)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0904
Application*: IH, F, WB
Datasheet SDS

Mouse Anti-CBX8 Recombinant Antibody (CBFYC-0903) (CBMAB-C0959-FY)

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Target: CBX8
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-0903
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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