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CCL1

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq]
Full Name
chemokine (C-C motif) ligand 1
Function
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Eosinophil chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: CAFA
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Positive regulation of inflammatory response Source: BHF-UCL
Positive regulation of interleukin-17 production Source: BHF-UCL
Positive regulation of monocyte chemotaxis Source: CAFA
Signal transduction Source: ProtInc
Viral process Source: ProtInc
Cellular Location
Secreted
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Anti-CCL1 antibodies

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Mouse Anti-CCL1 Recombinant Antibody (CBYY-C0040) (CBMAB-C0109-YY)

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Target: CCL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0040
Application*: N, E
Functional Assay
Datasheet SDS

Rat Anti-CCL1 Recombinant Antibody (148113) (CBMAB-C2975-LY)

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Target: CCL1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 148113
Application*: N, WB
Functional Assay
Datasheet SDS

Rat Anti-CCL1 Recombinant Antibody (148107) (CBMAB-C2974-LY)

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Target: CCL1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 148107
Application*: N, E
Functional Assay
Datasheet SDS

Rat Anti-CCL1 Recombinant Antibody (CBFYC-0919) (CBMAB-C0975-FY)

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Target: CCL1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYC-0919
Application*: N, WB
Functional Assay
Datasheet SDS

Rat Anti-CCL1 Recombinant Antibody (CBFYC-0918) (CBMAB-C0974-FY)

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Target: CCL1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-0918
Application*: N, WB
Functional Assay
Datasheet SDS

Mouse Anti-CCL1 Recombinant Antibody (CBFYC-0917) (CBMAB-C0973-FY)

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Target: CCL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0917
Application*: E, F
Datasheet SDS

Mouse Anti-CCL1 Recombinant Antibody (CBYY-I0916) (CBMAB-I2084-YY)

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Target: CCL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I0916
Application*: E
Datasheet SDS

Mouse Anti-CCL1 Recombinant Antibody (4E4) (CBMAB-C6869-LY)

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Target: CCL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4E4
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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