CCNA1

CCNA1 (Cyclin A1) is a Protein Coding gene. Diseases associated with CCNA1 include Myeloid Leukemia and Acute Promyelocytic Leukemia. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNA2.
Full Name
Cyclin A1
Function
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Biological Process
Cell division Source: UniProtKB-KW
Male meiosis I Source: ProtInc
Mitotic cell cycle phase transition Source: GO_Central
Protein deubiquitination Source: Reactome
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: Reactome
Spermatogenesis Source: ProtInc
Cellular Location
Nucleus
PTM
Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
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Anti-CCNA1 antibodies

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Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Cattle
Clone: E70.1
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: XLA1-1
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Frog
Clone: XLA1-3
Application*: WB, IP, E
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0051
Application*: E, IF
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 722407
Application*: WB, IH
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A11-5B5
Application*: E, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3F6B2C2
Application*: E, IF
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 06
Application*: F, IF
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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