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CCNA1

CCNA1 (Cyclin A1) is a Protein Coding gene. Diseases associated with CCNA1 include Myeloid Leukemia and Acute Promyelocytic Leukemia. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNA2.
Full Name
Cyclin A1
Function
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Biological Process
Cell division Source: UniProtKB-KW
Male meiosis I Source: ProtInc
Mitotic cell cycle phase transition Source: GO_Central
Protein deubiquitination Source: Reactome
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: Reactome
Spermatogenesis Source: ProtInc
Cellular Location
Nucleus
PTM
Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.

Anti-CCNA1 antibodies

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Target: CCNA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Application*: E, IF, IH, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1011
Application*: IH, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0051
Application*: F, IC, IF
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 06
Application*: F, IC/IF, IF
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 01
Application*: P
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12K76
Application*: C, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3F6B2C2
Application*: E, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A11-5B5
Application*: E, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 722407
Application*: WB, IH
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Cattle, Human, Monkey, Mouse, Rat
Clone: CBYY-C1104
Application*: E, IF, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1105
Application*: E, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1106
Application*: E, IH, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1107
Application*: WB, IH
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT10.2
Application*: IH, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: E43.2
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Cattle
Clone: E70.1
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: E72.1
Application*: IH, IF, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: XLA1-1
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-153
Application*: FC
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: E72.1
Application*: IF, IHC, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Cattle, Human, Mouse
Clone: CY-A1
Application*: ICC, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Cattle
Clone: E70.1
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: E43.2
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Cattle, Human, Mink, Mouse
Clone: E67.1
Application*: FC, IF, IHC, IP, WB
Target: CCNA1
Host: Mouse
Specificity: Human
Clone: CBFYC-1012
Application*: P
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT10.2
Application*: IHC, IP, WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: XLA1-3
Application*: WB
Target: CCNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: XLA1-1
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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