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CDCP1

CDCP1 (CUB Domain Containing Protein 1) is a Protein Coding gene. Diseases associated with CDCP1 include Colorectal Cancer. Among its related pathways are Wnt / Hedgehog / Notch and NF-kappaB Signaling.
Full Name
CUB Domain Containing Protein 1
Function
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Cellular Location
Isoform 1: Cell membrane. Shedding may also lead to a soluble peptide.
Isoform 3: Secreted
Topology
Extracellular: 30-667
Helical: 668-688
Cytoplasmic: 689-836
PTM
Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5.
N-glycosylated.
A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.

Anti-CDCP1 antibodies

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Mouse Anti-CDCP1 Recombinant Antibody (1A3) (CBMAB-0213CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A3
Application*: IP, WB

Mouse Anti-CDCP1 Recombinant Antibody (V2-6267) (CBMAB-0212CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-6267
Application*: MC, F, IP

Mouse Anti-CDCP1 Recombinant Antibody (CBXC-2612) (CBMAB-C5748-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Mouse
Clone: CBXC-2612
Application*: WB, F

Mouse Anti-CDCP1 Recombinant Antibody (CBXC-2240) (CBMAB-C5747-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2240
Application*: E

Mouse Anti-CDCP1 Recombinant Antibody (CBXC-2721) (CBMAB-C5746-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2721
Application*: WB, IH, IF, F

Mouse Anti-CDCP1 Recombinant Antibody (CBXC-1088) (CBMAB-C5745-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1088
Application*: WB, IP

Mouse Anti-CDCP1 Recombinant Antibody (CUB1) (CBMAB-C5744-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CUB1
Application*: F

Rat Anti-CDCP1 Recombinant Antibody (CBXC-1699) (CBMAB-C3591-CQ)

Datasheet SDS
Target: CDCP1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBXC-1699
Application*: E, WB

Human Anti-CDCP1 Recombinant Antibody (CBXC-0736) (CBMAB-C1850-CQ)

Datasheet SDS
Target: CDCP1
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0736
Application*: F

Mouse Anti-CDCP1 Recombinant Antibody (CBXC-1086) (CBMAB-C1352-CQ)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1086
Application*: F

Mouse Anti-CDCP1 Recombinant Antibody (CBFYC-1536) (CBMAB-C1595-FY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-1536
Application*: F

Rabbit Anti-CDCP1 Recombinant Antibody (CBFYC-1535) (CBMAB-C1594-FY)

Datasheet SDS
Target: CDCP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-1535
Application*: E

Mouse Anti-CDCP1 (AA 33-666) Recombinant Antibody (CBFYC-1534) (CBMAB-C1593-FY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1534
Application*: F

Rabbit Anti-CDCP1 Recombinant Antibody (EG579) (CBMAB-EN698-LY)

Datasheet SDS
Target: CDCP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG579
Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000

Rabbit Anti-CDCP1 Recombinant Antibody (D1W9N) (CBMAB-CP0257-LY)

Datasheet SDS
Target: CDCP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1W9N
Application*: WB, IP

Rabbit Anti-CDCP1 (Phosphorylated Y743) Recombinant Antibody (D2G2J) (PTM-CBMAB-0595LY)

Datasheet SDS
Target: CDCP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D2G2J
Application*: WB

Mouse Anti-CDCP1 Recombinant Antibody (12K58) (CBMAB-C2046-CN)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12K58
Application*: FC

Mouse Anti-CDCP1 Recombinant Antibody (CBYY-C1702) (CBMAB-C3140-YY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1702
Application*: P, WB

Mouse Anti-CDCP1 Recombinant Antibody (5B3) (CBMAB-C7316-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5B3
Application*: C, WB

Mouse Anti-CDCP1 Recombinant Antibody (4G5) (CBMAB-C6999-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G5
Application*: F, IF, WB

Mouse Anti-CDCP1 Recombinant Antibody (4F1) (CBMAB-C6899-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F1
Application*: WB

Rat Anti-CDCP1 Recombinant Antibody (469114) (CBMAB-C6511-LY)

Datasheet SDS
Target: CDCP1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 469114
Application*: WB

Mouse Anti-CDCP1 Recombinant Antibody (3B5) (CBMAB-C5727-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B5
Application*: P, WB

Mouse Anti-CDCP1 Recombinant Antibody (309137) (CBMAB-C5469-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 309137
Application*: IP, WB

Mouse Anti-CDCP1 Recombinant Antibody (2G2) (CBMAB-C5163-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G2
Application*: IF, WB

Mouse Anti-CDCP1 Recombinant Antibody (2C1) (CBMAB-C4739-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C1
Application*: F, IF, C, WB

Mouse Anti-CDCP1 Recombinant Antibody (2B8) (CBMAB-C4728-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B8
Application*: F

Mouse Anti-CDCP1 Recombinant Antibody (1D3A1) (CBMAB-C3823-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D3A1
Application*: F

Rabbit Anti-CDCP1 Recombinant Antibody (040) (CBMAB-C1756-LY)

Datasheet SDS
Target: CDCP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 040
Application*: E

Mouse Anti-CDCP1 Recombinant Antibody (309121) (CBMAB-C0938-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 309121
Application*: F, P, C

Mouse Anti-CDCP1 Recombinant Antibody (309112) (CBMAB-C0937-LY)

Datasheet SDS
Target: CDCP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 309112
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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