CDH12

CDH12 (Cadherin 12) is a Protein Coding gene. Diseases associated with CDH12 include Cri-Du-Chat Syndrome. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH6.
Full Name
Cadherin 12
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Biological Process
Adherens junction organization Source: GO_Central
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Source: GO_Central
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Cell-cell junction assembly Source: GO_Central
Cell morphogenesis Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Multicellular organism development Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 55-609
Helical: 610-637
Cytoplasmic: 638-794
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Anti-CDH12 antibodies

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Rabbit Anti-CDH12 Recombinant Antibody (403) (CBMAB-C6439-LY)

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Target: CDH12
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 403
Application*: E
Datasheet SDS

Mouse Anti-CDH12 Recombinant Antibody (1B4) (CBMAB-C3646-LY)

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Target: CDH12
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 1B4
Application*: E, WB
Datasheet SDS

Human Recombinant CDH12 protein, His Tag (V2LY-0526-LY3008)

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Target: CDH12
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-605
Tag: His Tag
Datasheet SDS

Rat Anti-CDH12 Recombinant Antibody (CBXC-1123) (CBMAB-C1389-CQ)

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Target: CDH12
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1123
Application*: WB, F, IF
Datasheet SDS

Mouse Anti-CDH12 Recombinant Antibody (CBFYC-0022) (CBMAB-C0028-FY)

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Target: CDH12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0022
Application*: E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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