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CNOT10

CNOT10 (CCR4-NOT Transcription Complex Subunit 10) is a Protein Coding gene. Among its related pathways are Gene Expression and Deadenylation-dependent mRNA decay.

Full Name

CNOT10

Function

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.

Biological Process

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Source: Reactome
Gene silencing by RNA Source: UniProtKB-KW
mRNA catabolic process Source: GO_Central
Negative regulation of translation Source: GO_Central
Nuclear-transcribed mRNA poly(A) tail shortening Source: Reactome

Cellular Location

Nucleus; Cytoplasm

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Anti-CNOT10 antibodies

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Mouse Anti-CNOT10 Recombinant Antibody (CBWJC-2862) (V2LY-1206-LY451)

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Target: CNOT10

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Mouse, Rat, Human

Clone: CBWJC-2862

Application*: WB, IP, IF, E

Mouse Anti-CNOT10 Recombinant Antibody (1D5) (V2LY-1206-LY450)

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Target: CNOT10

Host: Mouse

Antibody Isotype: IgG2c

Specificity: Human

Clone: 1D5

Application*: E, IP, WB, F, IF

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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