COTL1
COTL1 (Coactosin Like F-Actin Binding Protein 1) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include enzyme binding and actin binding.
Full Name
Coactosin Like F-Actin Binding Protein 1
Function
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Biological Process
Defense response to fungus Source: Ensembl
Neutrophil degranulation Source: Reactome
Regulation of actin filament polymerization Source: GO_Central
Neutrophil degranulation Source: Reactome
Regulation of actin filament polymerization Source: GO_Central
Cellular Location
Cytoplasm; Nucleus; Cytoskeleton
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Anti-COTL1 antibodies
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Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2110
Application*: E, IF, WB, IH
Target: COTL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0391
Application*: WB, E
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C7435
Application*: E, F, WB
Target: COTL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D6
Application*: WB, E, F
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2376
Application*: IH
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4406
Application*: F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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