COTL1

COTL1 (Coactosin Like F-Actin Binding Protein 1) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include enzyme binding and actin binding.
Full Name
Coactosin Like F-Actin Binding Protein 1
Function
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Biological Process
Defense response to fungus Source: Ensembl
Neutrophil degranulation Source: Reactome
Regulation of actin filament polymerization Source: GO_Central
Cellular Location
Cytoplasm; Nucleus; Cytoskeleton
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Anti-COTL1 antibodies

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Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2110
Application*: E, IF, WB, IH
Target: COTL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0391
Application*: WB, E
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C7435
Application*: E, F, WB
Target: COTL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D6
Application*: WB, E, F
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2376
Application*: IH
Target: COTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4406
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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