COTL1

COTL1 (Coactosin Like F-Actin Binding Protein 1) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include enzyme binding and actin binding.

Full Name

Coactosin Like F-Actin Binding Protein 1

Function

Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

Biological Process

Defense response to fungus Source: Ensembl
Neutrophil degranulation Source: Reactome
Regulation of actin filament polymerization Source: GO_Central

Cellular Location

Cytoplasm; Nucleus; Cytoskeleton

Anti-COTL1 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-COTL1 Recombinant Antibody (CBFYC-2110) (CBMAB-C2176-FY)

Datasheet

SDS

Target: COTL1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-2110

Application*: E, IF, WB, IH

Mouse Anti-COTL1 Recombinant Antibody (CBFYC-0391) (CBMAB-C0432-FY)

Datasheet

SDS

Target: COTL1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYC-0391

Application*: WB, E

Mouse Anti-COTL1 Recombinant Antibody (C7435) (CBMAB-C7435-LY)

Datasheet

SDS

Target: COTL1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: C7435

Application*: E, F, WB

Mouse Anti-COTL1 Recombinant Antibody (1D6) (CBMAB-C0504-LY)

Datasheet

SDS

Target: COTL1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1D6

Application*: WB, E, F

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)