COX5B

COX5B (Cytochrome C Oxidase Subunit 5B) is a Protein Coding gene. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Gene Expression. Gene Ontology (GO) annotations related to this gene include cytochrome-c oxidase activity.
Full Name
Cytochrome C Oxidase Subunit 5B
Function
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Biological Process
Mitochondrial electron transport, cytochrome c to oxygen Source: GO_Central
Respiratory gaseous exchange by respiratory system Source: ProtInc
Cellular Location
Mitochondrion inner membrane
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Anti-COX5B antibodies

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Human Recombinant COX5B protein, His Tag (V2LY-0526-LY3347)

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Target: COX5B
Expressed Host: E. coli
Sequence: Amino Acid: 32-129
Tag: His Tag
Datasheet SDS

Rabbit Anti-COX5B Recombinant Antibody (EG795) (V2LY-1206-LY876)

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Target: COX5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG795
Application*: E, F
Datasheet SDS

Mouse Anti-COX5B Recombinant Antibody (CBCNC-067) (V2LY-1206-LY875)

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Target: COX5B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-067
Application*: E, WB
Datasheet SDS

Mouse Anti-COX5B Recombinant Antibody (CBFYC-2125) (V2LY-1206-LY874)

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Target: COX5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2125
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-COX5B Recombinant Antibody (16H12H9) (V2LY-1206-LY873)

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Target: COX5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 16H12H9
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-COX5B Recombinant Antibody (C2201) (V2LY-1206-LY872)

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Target: COX5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: C2201
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-COX5B Recombinant Antibody (031) (V2LY-1206-LY871)

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Target: COX5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 031
Application*: E, P
Datasheet SDS

Rabbit Anti-COX5B Recombinant Antibody (021) (V2LY-1206-LY870)

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Target: COX5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 021
Application*: E, WB
Datasheet SDS

Rabbit Anti-COX5B Recombinant Antibody (020) (V2LY-1206-LY869)

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Target: COX5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 020
Application*: WB, E, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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