CPA1
CPA1 (Carboxypeptidase A1) is a Protein Coding gene. Diseases associated with CPA1 include Pancreatitis and Borna Disease. Among its related pathways are Collagen chain trimerization and Pancreatic secretion. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity and exopeptidase activity. An important paralog of this gene is CPA2.
Full Name
Carboxypeptidase A1
Function
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:8806703).
Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).
Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).
Biological Process
Leukotriene metabolic process Source: UniProtKB
Proteolysis Source: GO_Central
Proteolysis Source: GO_Central
Cellular Location
Secreted
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Anti-CPA1 antibodies
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Target: CPA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0246
Application*: WB, P
Target: CPA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-2131
Application*: E, IP, WB
Target: CPA1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-419
Tag: His Tag
Target: CPA1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2236
Application*: WB, IP
Target: CPA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-2136
Application*: P
Target: CPA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2134
Application*: E
Target: CPA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-2133
Application*: WB, P
Target: CPA1
Host: Mouse
Antibody Isotype: IgG2c, κ
Specificity: Human, Cattle
Clone: CBFYC-2132
Application*: WB, P
Target: CPA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 001
Application*: E
Target: CPA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 03
Application*: P
Target: CPA1
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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