CPE

CPE (Carboxypeptidase E) is a Protein Coding gene. Diseases associated with CPE include Hyperproinsulinemia and Phlebotomus Fever. Among its related pathways are Peptide hormone metabolism and Allograft rejection. Gene Ontology (GO) annotations related to this gene include cell adhesion molecule binding and carboxypeptidase activity. An important paralog of this gene is CPD.
Full Name
Carboxypeptidase E
Function
Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
Biological Process
Cardiac left ventricle morphogenesis Source: BHF-UCL
Cellular protein modification process Source: UniProtKB
Neuropeptide signaling pathway Source: UniProtKB
Peptide metabolic process Source: GO_Central
Protein localization to membrane Source: BHF-UCL
Protein processing Source: GO_Central
Wnt signaling pathway Source: CACAO
Cellular Location
Isoform 1: Secreted; Secretory vesicle; Secretory vesicle membrane. Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
View more

Anti-CPE antibodies

+ Filters
Loading...
Target: CPE
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2156
Application*: E
Target: CPE
Sensitivity: 0.01 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cpe
Sensitivity: 0.0031 ng/mL
Detection Range: 0.007-1.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CPE
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-453
Tag: His Tag
Target: CPE
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-453
Tag: hFc Tag
Target: CPE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat, Human, Mouse, Horse, Cattle, Dog, Pig
Clone: CBXC-1179
Application*: WB, IP, IF, E
Target: CPE
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat, Human, Mouse, Horse, Cattle, Dog, Pig
Clone: CBYY-C0036
Application*: WB, IP, IF, E
Target: CPE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: C6461
Application*: P, IP, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.