CUEDC2

CUEDC2 (CUE Domain Containing 2) is a Protein Coding gene. Among its related pathways are DNA Damage.
Full Name
CUE domain containing 2
Function
Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
Biological Process
Negative regulation of cytokine production involved in inflammatory response Source: MGI
Negative regulation of macrophage cytokine production Source: MGI
Cellular Location
Nucleus; Cytoplasm
Involvement in disease
May predict the clinical outcome of tamoxifen therapy of breast cancer patients. Patients with tumors that highly express CUEDC2 do not respond to tamoxifen treatment as effectively as those with tumors with low expression.
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Anti-CUEDC2 antibodies

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Mouse Anti-CUEDC2 Recombinant Antibody (CBFYC-2470) (V2LY-0125-LY515)

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Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2470
Application*: E
Datasheet SDS

Rabbit Anti-CUEDC2 Recombinant Antibody (CBFYC-2469) (V2LY-0125-LY514)

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Target: CUEDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2469
Application*: E, P
Datasheet SDS

Mouse Anti-CUEDC2 Recombinant Antibody (2B11) (V2LY-0125-LY513)

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Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2B11
Application*: E, WB
Datasheet SDS

Mouse Anti-CUEDC2 Recombinant Antibody (01) (V2LY-0125-LY512)

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Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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