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CUEDC2

CUEDC2 (CUE Domain Containing 2) is a Protein Coding gene. Among its related pathways are DNA Damage.
Full Name
CUE domain containing 2
Function
Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
Biological Process
Negative regulation of cytokine production involved in inflammatory response Source: MGI
Negative regulation of macrophage cytokine production Source: MGI
Cellular Location
Nucleus; Cytoplasm
Involvement in disease
May predict the clinical outcome of tamoxifen therapy of breast cancer patients. Patients with tumors that highly express CUEDC2 do not respond to tamoxifen treatment as effectively as those with tumors with low expression.

Anti-CUEDC2 antibodies

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Mouse Anti-CUEDC2 Recombinant Antibody (CBWJC-3448) (CBMAB-C4678WJ)

Datasheet SDS
Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3448
Application*: WB

Mouse Anti-CUEDC2 Recombinant Antibody (CBFYC-2470) (CBMAB-C2543-FY)

Datasheet SDS
Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2470
Application*: F

Rabbit Anti-CUEDC2 Recombinant Antibody (CBFYC-2469) (CBMAB-C2542-FY)

Datasheet SDS
Target: CUEDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2469
Application*: E, P

Rabbit Anti-CUEDC2 Recombinant Antibody (CBCNC-500) (CBMAB-C3175-CN)

Datasheet SDS
Target: CUEDC2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-500
Application*: E, P

Mouse Anti-CUEDC2 Recombinant Antibody (2B11) (CBMAB-C4660-LY)

Datasheet SDS
Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2B11
Application*: E, WB

Mouse Anti-CUEDC2 Recombinant Antibody (01) (CBMAB-C1583-LY)

Datasheet SDS
Target: CUEDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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