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CXCL2

CXCL2 (C-X-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases associated with CXCL2 include Pneumonia and Peritonitis. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include chemokine activity and CXCR chemokine receptor binding. An important paralog of this gene is CXCL1.
Full Name
chemokine (C-X-C motif) ligand 2
Function
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cellular response to lipopolysaccharide Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytokine-mediated signaling pathway Source: Reactome
G protein-coupled receptor signaling pathway Source: Reactome
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Neutrophil chemotaxis Source: GO_Central
Response to molecule of bacterial origin Source: BHF-UCL
Cellular Location
Secreted
PTM
The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.

Anti-CXCL2 antibodies

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Mouse Anti-CXCL2 Recombinant Antibody (MM0214-11B27) (CBMAB-G1496-LY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0214-11B27
Application*: WB

Rat Anti-CXCL2 Recombinant Antibody (RM0209-13N6) (CBMAB-G1497-LY)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0209-13N6
Application*: WB

Mouse Anti-CXCL2 Recombinant Antibody (11B27) (CBMAB-C2479-LY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11B27
Application*: WB, N

Mouse Anti-CXCL2 Recombinant Antibody (14L315) (CBMAB-C3218-CN)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L315
Application*: N, WB

Mouse Anti-CXCL2 Recombinant Antibody (CBFYM-1060) (CBMAB-M1213-FY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-1060
Application*: E, WB

Mouse Anti-CXCL2 Recombinant Antibody (CBFYM-1061) (CBMAB-M1214-FY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-1061
Application*: E, WB

Mouse Anti-CXCL2 Recombinant Antibody (123802) (CBMAB-C2586-LY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: 123802
Application*: WB, N, EC

Rat Anti-CXCL2 Recombinant Antibody (13N6) (CBMAB-C2952-LY)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 13N6
Application*: N, WB

Rabbit Anti-CXCL2 Recombinant Antibody (16H3L10) (CBMAB-C3376-LY)

Datasheet SDS
Target: CXCL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Mouse
Clone: 16H3L10
Application*: P, WB

Rat Anti-CXCL2 Recombinant Antibody (40605) (CBMAB-C6445-LY)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 40605
Application*: ED, N, WB

Mouse Anti-CXCL2 Recombinant Antibody (CBFYC-2513) (CBMAB-C2587-FY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2513
Application*: WB, N

Rat Anti-CXCL2 Recombinant Antibody (CBFYC-2514) (CBMAB-C2588-FY)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2514
Application*: N, WB

Mouse Anti-CXCL2 Recombinant Antibody (CBFYC-2515) (CBMAB-C2589-FY)

Datasheet SDS
Target: CXCL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBFYC-2515
Application*: WB, N, EC

Rabbit Anti-CXCL2 (AA 32-100) Recombinant Antibody (CBFYC-2516) (CBMAB-C2590-FY)

Datasheet SDS
Target: CXCL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBFYC-2516
Application*: IH, WB

Rat Anti-CXCL2 Recombinant Antibody (CBYY-C0210) (CBMAB-C0602-YY)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-C0210
Application*: E(Det), WB, N, E(Cap)

Rat Anti-CXCL2 Recombinant Antibody (CBXC-1496) (CBMAB-C3335-CQ)

Datasheet SDS
Target: CXCL2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-1496
Application*: N, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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