DLGAP5

DLGAP5 (DLG Associated Protein 5) is a Protein Coding gene. Among its related pathways are Aurora A signaling. Gene Ontology (GO) annotations related to this gene include phosphoprotein phosphatase activity. An important paralog of this gene is DLGAP1.
Full Name
DLG Associated Protein 5
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Biological Process
Centrosome localization Source: GO_Central
Chromosome segregation Source: GO_Central
Kinetochore assembly Source: GO_Central
Mitotic chromosome movement towards spindle pole Source: UniProtKB
Mitotic spindle organization Source: GO_Central
Positive regulation of mitotic metaphase/anaphase transition Source: UniProtKB
Regulation of mitotic cell cycle Source: GO_Central
Signaling Source: InterPro
Cellular Location
Spindle; Nucleus; Cytoplasm. Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
PTM
Ubiquitinated, leading to its degradation.
Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
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Anti-DLGAP5 antibodies

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Rabbit Anti-DLGAP5 Recombinant Antibody (EG968) (CBMAB-EN1150-LY)

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Target: DLGAP5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG968
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Datasheet SDS

Human DLGAP5 ELISA Kit (V2LY-0626-LY3335)

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Target: DLGAP5
Sensitivity: 0.31 ng/mL
Detection Range: 0.5-300 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Anti-DLGAP5 Recombinant Antibody (EG968) (V2LY-0425-LY466)

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Target: DLGAP5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: EG968
Application*: WB, IP, IF, E, P
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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